Salivary cell-free DNA methylation analysis for oncological monitoring of surgical resection of oral squamous cell carcinoma

Salivary cell-free DNA methylation analysis for oncological monitoring of surgical resection of oral squamous cell carcinoma

ObjectiveNon-invasive analysis of tumor DNA in biological fluids offers promising perspectives for the oncological monitoring of cancer patients. Cancer-specific DNA methylation marks are detectable in the saliva of Oral Squamous Cell Carcinoma (OSCC) patients. We set up a salivary liquid biopsy app...

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Bibliographic Details
Main Authors: Zuzana Saidak, Marie Milly, Christophe Louandre, Emilien Colin, Pia-Manuela Rusu, Agnes Paasche, Stephanie Dakpe, Sylvie Testelin, Antoine Galmiche
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oral Health
Subjects:
oral squamous cell carcinoma
surgical resection
saliva
cell-free DNA methylation
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/froh.2025.1614371/full
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