KSHV miRNAs target STING to evade innate immunity and facilitate KSHV lytic reactivation from latency

KSHV miRNAs target STING to evade innate immunity and facilitate KSHV lytic reactivation from latency

Summary: Kaposi sarcoma-associated herpesvirus (KSHV) employs various strategies to evade host immune surveillance and maintain lifelong latency. The cyclic GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) DNA sensing pathway is a key innate immunity pathway that detects viral DNA and...

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Bibliographic Details
Main Authors: Kimberly Paulsen, Rosenna Chan, Lauren Gay, Zhe Ma
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725005121
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