Long non-coding RNA NORAD serves as a promoter of oncogenesis and inhibits ferroptosis via miR-144-3p-mTOR-ferritinophagy axis in cancer

Long non-coding RNA NORAD serves as a promoter of oncogenesis and inhibits ferroptosis via miR-144-3p-mTOR-ferritinophagy axis in cancer

Abstract Non-coding RNA activated by DNA damage (NORAD) has been found to enhance proliferation and metastasis of cancer cells. Ferroptosis is characterized by excess lipid peroxidation and has been confirmed to eliminate cancer cells. However, the specific role of NORAD in cancer and ferroptosis is...

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Bibliographic Details
Main Authors: Xuefei Zhang, Wei Zheng, Haixia Li, Lei Zhang, Haidong Zhao, Shiyao Sui, Wen Cheng
Format: Article
Language:English
Published: BMC 2025-08-01
Series:European Journal of Medical Research
Subjects:
Ferroptosis
Non-coding RNA activated by DNA damage
Cancer
MicroRNA
Online Access:https://doi.org/10.1186/s40001-025-02998-2
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