Faecal mucoprotein MUC2 is decreased in multiple sclerosis and is associated with mucin degrading bacteriaResearch in context
Summary: Background: The gut microbiome is altered in MS and may contribute to disease by disrupting the intestinal barrier. The colonic mucus barrier, which is primarily composed of mucin protein 2 (MUC2), plays a crucial role in providing a barrier between colonic epithelial cells and the microbi...
Saved in:
| Main Authors: | Luke A. Schwerdtfeger, Federico Montini, Tanuja Chitnis, Laura M. Cox, Howard L. Weiner |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
|
| Series: | EBioMedicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396425001653 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Using MUC2 mucin producing tumorigenic human goblet-like cells to uncover functional properties of the mucus barrier
by: Hayley Gorman, et al.
Published: (2025-12-01) -
Brain microvascular endothelial cells differentiated from a Friedreich’s Ataxia patient iPSC are deficient in tight junction protein expression and paracellularly permeable
by: Frances M. Smith, et al.
Published: (2025-04-01) -
The Improvement of Intestinal Mucosal Epithelial Barrier Integrity by 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone in Rat Experimental Colitis
by: Szandruk-Bender M, et al.
Published: (2025-07-01) -
A mucus layer derived from porcine intestinal organoid air–liquid interface monolayer attenuates swine enteric coronavirus infection by antiviral activity of Muc2
by: Ning Yang, et al.
Published: (2024-12-01) -
The effect of 8 weeks of quercetin supplementation and intermittent exercise on gene expression of Muc5Ac, Muc4 and polyphosphate in rats with colon cancer
by: Shahin Heydari, et al.
Published: (2023-01-01)