EVALUATION OF POTENTIAL RISK POSED BY MEDICATIONS TO THE FETUS

The article focuses on the issue of evaluating potential risk posed by medications to the fetus during pregnancy. For this purpose various countries use classifications of medications broken down into risk categories during pregnancy. The most popular classification is US FDA classification, which i...

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Main Authors: S.A. Sher, A.V. Ostrovskaya
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2010-05-01
Series:Педиатрическая фармакология
Online Access:https://www.pedpharma.ru/jour/article/view/1149
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author S.A. Sher
A.V. Ostrovskaya
author_facet S.A. Sher
A.V. Ostrovskaya
author_sort S.A. Sher
collection DOAJ
description The article focuses on the issue of evaluating potential risk posed by medications to the fetus during pregnancy. For this purpose various countries use classifications of medications broken down into risk categories during pregnancy. The most popular classification is US FDA classification, which identifies five categories of medications (А, В, С, D and Х) depending on the degree of their embryotoxic and teratogenic side effect, which enables physicians to make informed choices in selecting pharmacotherapy during the entire gestational period. The article discusses possible specific fetal and neonatal disorders when administering medications in categories X and D. Medications in category D may be prescribed to pregnant women only in extreme situations. Administering medications in category X is absolutely inadvisable before and during pregnancy. Further research in this area makes it possible to improve the classification of medications by degree of their embryotoxic and teratogenic risk and address the issue of selecting safe medications during pregnancy. Key words: medications, gestational period, embryo, fetus, embryotoxic and teratogenic action, fetal and neonatal disorders. (Pediatric Pharmacology. – 2010; 7(3):78-81)
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spelling doaj-art-87fbc9a6298e4e61ae5c311e2d0f1f0e2025-08-20T03:19:42ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892010-05-017378811144EVALUATION OF POTENTIAL RISK POSED BY MEDICATIONS TO THE FETUSS.A. Sher0A.V. Ostrovskaya1Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowThe article focuses on the issue of evaluating potential risk posed by medications to the fetus during pregnancy. For this purpose various countries use classifications of medications broken down into risk categories during pregnancy. The most popular classification is US FDA classification, which identifies five categories of medications (А, В, С, D and Х) depending on the degree of their embryotoxic and teratogenic side effect, which enables physicians to make informed choices in selecting pharmacotherapy during the entire gestational period. The article discusses possible specific fetal and neonatal disorders when administering medications in categories X and D. Medications in category D may be prescribed to pregnant women only in extreme situations. Administering medications in category X is absolutely inadvisable before and during pregnancy. Further research in this area makes it possible to improve the classification of medications by degree of their embryotoxic and teratogenic risk and address the issue of selecting safe medications during pregnancy. Key words: medications, gestational period, embryo, fetus, embryotoxic and teratogenic action, fetal and neonatal disorders. (Pediatric Pharmacology. – 2010; 7(3):78-81)https://www.pedpharma.ru/jour/article/view/1149
spellingShingle S.A. Sher
A.V. Ostrovskaya
EVALUATION OF POTENTIAL RISK POSED BY MEDICATIONS TO THE FETUS
Педиатрическая фармакология
title EVALUATION OF POTENTIAL RISK POSED BY MEDICATIONS TO THE FETUS
title_full EVALUATION OF POTENTIAL RISK POSED BY MEDICATIONS TO THE FETUS
title_fullStr EVALUATION OF POTENTIAL RISK POSED BY MEDICATIONS TO THE FETUS
title_full_unstemmed EVALUATION OF POTENTIAL RISK POSED BY MEDICATIONS TO THE FETUS
title_short EVALUATION OF POTENTIAL RISK POSED BY MEDICATIONS TO THE FETUS
title_sort evaluation of potential risk posed by medications to the fetus
url https://www.pedpharma.ru/jour/article/view/1149
work_keys_str_mv AT sasher evaluationofpotentialriskposedbymedicationstothefetus
AT avostrovskaya evaluationofpotentialriskposedbymedicationstothefetus