Selective Depletion of Regulatory T Cell Subsets by Docetaxel Treatment in Patients with Nonsmall Cell Lung Cancer

Selective Depletion of Regulatory T Cell Subsets by Docetaxel Treatment in Patients with Nonsmall Cell Lung Cancer

Regulatory T (Treg) cells are potent suppressors that maintain immune homeostasis. Accumulation of Treg can inhibit effective immune responses in cancer patients, leading to tumor development and progression. Despite direct cytotoxicity, several chemotherapeutic drugs have been reported to deplete T...

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Bibliographic Details
Main Authors:	Jie-Yao Li, Xiu-Fang Duan, Li-Ping Wang, Yu-Jie Xu, Lan Huang, Teng-Fei Zhang, Jin-Yan Liu, Feng Li, Zhen Zhang, Dong-Li Yue, Fei Wang, Bin Zhang, Yi Zhang
Format:	Article
Language:	English
Published:	Wiley 2014-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2014/286170
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