Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural Setting

Background. Fine needle aspiration (FNA) remains the first-line diagnostic in management of thyroid nodules and reduces unnecessary surgeries. However, it is still challenging since cytological results are not always straightforward. This study aimed to examine the results of thyroid FNA using the B...

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Main Authors: Aili Guo, Yuuki Kaminoh, Terra Forward, Frank L. Schwartz, Scott Jenkinson
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2017/9601735
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author Aili Guo
Yuuki Kaminoh
Terra Forward
Frank L. Schwartz
Scott Jenkinson
author_facet Aili Guo
Yuuki Kaminoh
Terra Forward
Frank L. Schwartz
Scott Jenkinson
author_sort Aili Guo
collection DOAJ
description Background. Fine needle aspiration (FNA) remains the first-line diagnostic in management of thyroid nodules and reduces unnecessary surgeries. However, it is still challenging since cytological results are not always straightforward. This study aimed to examine the results of thyroid FNA using the Bethesda system for reporting thyroid cytopathology (TBSRTC) to establish the level of accuracy of FNA procedures in a rural practice setting. Method. A retrospective chart review was conducted on existing thyroid FNA performed in a referral endocrine center between December 2011 and November 2015. Results. A total of 159 patients (18–88 years old) and 236 nodule aspirations were performed and submitted for evaluation. 79% were benign, 3% atypia/follicular lesion of unknown significance (AUS/FLUS), 5% follicular neoplasm/suspicious for follicular neoplasm (FN/SFN), 4% suspicious for malignancy (one case was indeed an atypical parathyroid neoplasm by surgical pathology), 2% malignant, and 7% nondiagnostic. Two cases also had advanced molecular analysis on FNA specimens before thyroidectomy. Conclusion. The diagnostic yield of FNA cytology from our practice in a rural setting suggests that accuracy and specificity are comparable to results from larger centers.
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spelling doaj-art-87f1838255764eb5a1bb7593b5be75762025-08-20T02:09:24ZengWileyInternational Journal of Endocrinology1687-83371687-83452017-01-01201710.1155/2017/96017359601735Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural SettingAili Guo0Yuuki Kaminoh1Terra Forward2Frank L. Schwartz3Scott Jenkinson4Ohio University-Heritage College of Osteopathic Medicine, Athens, OH 45701, USAOhio University-Heritage College of Osteopathic Medicine, Athens, OH 45701, USAOhio University-Heritage College of Osteopathic Medicine, Athens, OH 45701, USAOhio University-Heritage College of Osteopathic Medicine, Athens, OH 45701, USAOhio University-Heritage College of Osteopathic Medicine, Athens, OH 45701, USABackground. Fine needle aspiration (FNA) remains the first-line diagnostic in management of thyroid nodules and reduces unnecessary surgeries. However, it is still challenging since cytological results are not always straightforward. This study aimed to examine the results of thyroid FNA using the Bethesda system for reporting thyroid cytopathology (TBSRTC) to establish the level of accuracy of FNA procedures in a rural practice setting. Method. A retrospective chart review was conducted on existing thyroid FNA performed in a referral endocrine center between December 2011 and November 2015. Results. A total of 159 patients (18–88 years old) and 236 nodule aspirations were performed and submitted for evaluation. 79% were benign, 3% atypia/follicular lesion of unknown significance (AUS/FLUS), 5% follicular neoplasm/suspicious for follicular neoplasm (FN/SFN), 4% suspicious for malignancy (one case was indeed an atypical parathyroid neoplasm by surgical pathology), 2% malignant, and 7% nondiagnostic. Two cases also had advanced molecular analysis on FNA specimens before thyroidectomy. Conclusion. The diagnostic yield of FNA cytology from our practice in a rural setting suggests that accuracy and specificity are comparable to results from larger centers.http://dx.doi.org/10.1155/2017/9601735
spellingShingle Aili Guo
Yuuki Kaminoh
Terra Forward
Frank L. Schwartz
Scott Jenkinson
Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural Setting
International Journal of Endocrinology
title Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural Setting
title_full Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural Setting
title_fullStr Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural Setting
title_full_unstemmed Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural Setting
title_short Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural Setting
title_sort fine needle aspiration of thyroid nodules using the bethesda system for reporting thyroid cytopathology an institutional experience in a rural setting
url http://dx.doi.org/10.1155/2017/9601735
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