Macrophage Notch1 Participates in LPS-Induced Acute Lung Injury via Regulating CCR5 Expression in Mice

Macrophage Notch1 Participates in LPS-Induced Acute Lung Injury via Regulating CCR5 Expression in Mice

Background: As pivotal immunoregulatory sentinels in pulmonary defense systems, alveolar macrophages (AMs) play dual roles in mediating inflammatory responses and tissue repair processes during various phases of inflammatory cascades. The present investigation focuses on elucidati...

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Bibliographic Details
Main Authors: Ruiyu Zhang, Hui Du, Zhi Liu, Yuxi Lei, Huizhi Hu, Junwen Zheng, Pu Yang, Dongchi Zhao
Format: Article
Language:English
Published: IMR Press 2025-04-01
Series:Frontiers in Bioscience-Landmark
Subjects:
acute lung injury
alveolar macrophages
notch
ccr5
cell migration
Online Access:https://www.imrpress.com/journal/FBL/30/4/10.31083/FBL37430
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