S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

Abstract Depression, a pervasive mental health condition, has increasingly been linked to neuroinflammation, as evidenced by elevated levels of pro‐inflammatory markers such as TNF‐α and IL‐1β observed in patients, which underscores the role of inflammation in its pathophysiology. This study investi...

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Bibliographic Details
Main Authors: Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
Depression
Neuroinflammation
R‐ketamine
SIRT2
S‐ketamine
Online Access:https://doi.org/10.1002/advs.202416481
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