Unlocking the potential of engineered immune cell therapy for solid tumors
Adoptive cell therapy has emerged as a promising approach for treating advanced solid malignancies. Genetic engineering techniques represent an exciting area of research for the development of cellular products with enhanced cytotoxicity, phenotype, and metabolism.
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-56527-0 |
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| _version_ | 1832571528321957888 |
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| author | Víctor Albarrán-Fernández Laura Angelats Julio Delgado Alena Gros Álvaro Urbano-Ispizua Sònia Guedan Aleix Prat |
| author_facet | Víctor Albarrán-Fernández Laura Angelats Julio Delgado Alena Gros Álvaro Urbano-Ispizua Sònia Guedan Aleix Prat |
| author_sort | Víctor Albarrán-Fernández |
| collection | DOAJ |
| description | Adoptive cell therapy has emerged as a promising approach for treating advanced solid malignancies. Genetic engineering techniques represent an exciting area of research for the development of cellular products with enhanced cytotoxicity, phenotype, and metabolism. |
| format | Article |
| id | doaj-art-87e7c28d952649038ad306c7696c5748 |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-87e7c28d952649038ad306c7696c57482025-02-02T12:33:12ZengNature PortfolioNature Communications2041-17232025-01-011611510.1038/s41467-025-56527-0Unlocking the potential of engineered immune cell therapy for solid tumorsVíctor Albarrán-Fernández0Laura Angelats1Julio Delgado2Alena Gros3Álvaro Urbano-Ispizua4Sònia Guedan5Aleix Prat6Medical Oncology Department, Hospital ClínicMedical Oncology Department, Hospital ClínicOncoimmunotherapy Unit, Department of Hematology, Hospital ClínicTumor Immunology and Immunotherapy, Vall d’Hebron Institute of Oncology (VHIO), Vall d’Hebron Hospital CampusOncoimmunotherapy Unit, Department of Hematology, Hospital ClínicCellular Immunotherapies for Cancer, August Pi I Sunyer Biomedical Research Institute (IDIBAPS)Medical Oncology Department, Hospital ClínicAdoptive cell therapy has emerged as a promising approach for treating advanced solid malignancies. Genetic engineering techniques represent an exciting area of research for the development of cellular products with enhanced cytotoxicity, phenotype, and metabolism.https://doi.org/10.1038/s41467-025-56527-0 |
| spellingShingle | Víctor Albarrán-Fernández Laura Angelats Julio Delgado Alena Gros Álvaro Urbano-Ispizua Sònia Guedan Aleix Prat Unlocking the potential of engineered immune cell therapy for solid tumors Nature Communications |
| title | Unlocking the potential of engineered immune cell therapy for solid tumors |
| title_full | Unlocking the potential of engineered immune cell therapy for solid tumors |
| title_fullStr | Unlocking the potential of engineered immune cell therapy for solid tumors |
| title_full_unstemmed | Unlocking the potential of engineered immune cell therapy for solid tumors |
| title_short | Unlocking the potential of engineered immune cell therapy for solid tumors |
| title_sort | unlocking the potential of engineered immune cell therapy for solid tumors |
| url | https://doi.org/10.1038/s41467-025-56527-0 |
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