Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis

A 56-year-old male with a history of seropositive rheumatoid arthritis complained of polyarthritis and forgetfulness. The initial CT scan of the head without contrast was negative for acute pathologies. However, as he continued to decline despite being on oral prednisone, an MRI of the head was orde...

Full description

Saved in:
Bibliographic Details
Main Authors: Pablo Weilg, Giancarlo Diaz-Zamora, Larry Young
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2020/8844951
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850213321616130048
author Pablo Weilg
Giancarlo Diaz-Zamora
Larry Young
author_facet Pablo Weilg
Giancarlo Diaz-Zamora
Larry Young
author_sort Pablo Weilg
collection DOAJ
description A 56-year-old male with a history of seropositive rheumatoid arthritis complained of polyarthritis and forgetfulness. The initial CT scan of the head without contrast was negative for acute pathologies. However, as he continued to decline despite being on oral prednisone, an MRI of the head was ordered and revealed a subtle small region of acute infarction in the left mammillary body. He was diagnosed with granulomatosis with polyangiitis in light of his positive C-ANCA antibodies, PR3 antibody, and a kidney biopsy, which showed focal necrotizing pauci-immune crescentic glomerulonephritis. Despite undergoing steroid pulse therapy, the patient developed diffuse alveolar damage which finally responded to rituximab infusion.
format Article
id doaj-art-87e5ea72ff464e938acba2c38f2ba4aa
institution OA Journals
issn 2090-6889
2090-6897
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Case Reports in Rheumatology
spelling doaj-art-87e5ea72ff464e938acba2c38f2ba4aa2025-08-20T02:09:09ZengWileyCase Reports in Rheumatology2090-68892090-68972020-01-01202010.1155/2020/88449518844951Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with PolyangiitisPablo Weilg0Giancarlo Diaz-Zamora1Larry Young2MercyOne North Iowa Medical Center, 1000 4th St SW, Mason City, IA 50401, USAMercyOne North Iowa Medical Center, 1000 4th St SW, Mason City, IA 50401, USAUniversity of Miami, Division of Rheumatology, 1120 NW 14th St, Miami, FL 33136, USAA 56-year-old male with a history of seropositive rheumatoid arthritis complained of polyarthritis and forgetfulness. The initial CT scan of the head without contrast was negative for acute pathologies. However, as he continued to decline despite being on oral prednisone, an MRI of the head was ordered and revealed a subtle small region of acute infarction in the left mammillary body. He was diagnosed with granulomatosis with polyangiitis in light of his positive C-ANCA antibodies, PR3 antibody, and a kidney biopsy, which showed focal necrotizing pauci-immune crescentic glomerulonephritis. Despite undergoing steroid pulse therapy, the patient developed diffuse alveolar damage which finally responded to rituximab infusion.http://dx.doi.org/10.1155/2020/8844951
spellingShingle Pablo Weilg
Giancarlo Diaz-Zamora
Larry Young
Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis
Case Reports in Rheumatology
title Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis
title_full Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis
title_fullStr Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis
title_full_unstemmed Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis
title_short Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis
title_sort amnesia in a patient with rheumatoid arthritis a case of granulomatosis with polyangiitis
url http://dx.doi.org/10.1155/2020/8844951
work_keys_str_mv AT pabloweilg amnesiainapatientwithrheumatoidarthritisacaseofgranulomatosiswithpolyangiitis
AT giancarlodiazzamora amnesiainapatientwithrheumatoidarthritisacaseofgranulomatosiswithpolyangiitis
AT larryyoung amnesiainapatientwithrheumatoidarthritisacaseofgranulomatosiswithpolyangiitis