Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds
Only a few studies have examined how pore geometry affects the mechanical characteristics, biological behavior, and degradation of additively manufactured biodegradable porous magnesium. In this work, the effects of pore geometry on mechanical qualities, degradation, and biological behavior were inv...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2024-11-01
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| Series: | Journal of Magnesium and Alloys |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S221395672300186X |
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| author | Chaoxin Wang Shuyuan Min Jinge Liu Bingchuan Liu Bo Peng Caimei Wang Xiaolin Ma Peng Wen Yufeng Zheng Yun Tian |
| author_facet | Chaoxin Wang Shuyuan Min Jinge Liu Bingchuan Liu Bo Peng Caimei Wang Xiaolin Ma Peng Wen Yufeng Zheng Yun Tian |
| author_sort | Chaoxin Wang |
| collection | DOAJ |
| description | Only a few studies have examined how pore geometry affects the mechanical characteristics, biological behavior, and degradation of additively manufactured biodegradable porous magnesium. In this work, the effects of pore geometry on mechanical qualities, degradation, and biological behavior were investigated using three typical porous architectures with the same porosity. The porous structures were found to satisfy bone tissue engineering requirements because they had sufficient degradation resistance and tunable compressive characteristics. All three types of magnesium alloy scaffolds exhibited good biocompatibility. Additionally, the magnesium alloy porous structures influenced the magnesium scaffold material degradation rate and the surrounding environment, impacting the osteogenic differentiation of bone mesenchymal stem cells and bone tissue regeneration. This work offers conceptual support for optimizing pore geometry to alter the mechanical and degradable characteristics of additively manufactured porous magnesium to meet therapeutic demands. |
| format | Article |
| id | doaj-art-87dc0aa55657408ebbcff48462acc24d |
| institution | Kabale University |
| issn | 2213-9567 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Journal of Magnesium and Alloys |
| spelling | doaj-art-87dc0aa55657408ebbcff48462acc24d2025-01-05T04:28:01ZengKeAi Communications Co., Ltd.Journal of Magnesium and Alloys2213-95672024-11-01121145094520Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffoldsChaoxin Wang0Shuyuan Min1Jinge Liu2Bingchuan Liu3Bo Peng4Caimei Wang5Xiaolin Ma6Peng Wen7Yufeng Zheng8Yun Tian9Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China; Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, ChinaDepartment of Orthopedics, Peking University Third Hospital, Beijing 100191, China; Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, ChinaDepartment of Mechanical Engineering, Tsinghua University, Beijing 100084, ChinaDepartment of Orthopedics, Peking University Third Hospital, Beijing 100191, China; Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, ChinaDepartment of Mechanical Engineering, Tsinghua University, Beijing 100084, ChinaBeijing AKEC Medical Co., Ltd., Beijing 102200, ChinaBeijing AKEC Medical Co., Ltd., Beijing 102200, ChinaDepartment of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Corresponding authors.School of Materials Science and Engineering, Peking University, Beijing 100871, China; Corresponding authors.Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China; Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, China; Corresponding author at: Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.Only a few studies have examined how pore geometry affects the mechanical characteristics, biological behavior, and degradation of additively manufactured biodegradable porous magnesium. In this work, the effects of pore geometry on mechanical qualities, degradation, and biological behavior were investigated using three typical porous architectures with the same porosity. The porous structures were found to satisfy bone tissue engineering requirements because they had sufficient degradation resistance and tunable compressive characteristics. All three types of magnesium alloy scaffolds exhibited good biocompatibility. Additionally, the magnesium alloy porous structures influenced the magnesium scaffold material degradation rate and the surrounding environment, impacting the osteogenic differentiation of bone mesenchymal stem cells and bone tissue regeneration. This work offers conceptual support for optimizing pore geometry to alter the mechanical and degradable characteristics of additively manufactured porous magnesium to meet therapeutic demands.http://www.sciencedirect.com/science/article/pii/S221395672300186XPore geometryAdditive manufacturingWE43 alloyMagnesium alloy |
| spellingShingle | Chaoxin Wang Shuyuan Min Jinge Liu Bingchuan Liu Bo Peng Caimei Wang Xiaolin Ma Peng Wen Yufeng Zheng Yun Tian Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds Journal of Magnesium and Alloys Pore geometry Additive manufacturing WE43 alloy Magnesium alloy |
| title | Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds |
| title_full | Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds |
| title_fullStr | Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds |
| title_full_unstemmed | Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds |
| title_short | Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds |
| title_sort | effect of pore geometry on properties of high temperature oxidized additively manufactured magnesium scaffolds |
| topic | Pore geometry Additive manufacturing WE43 alloy Magnesium alloy |
| url | http://www.sciencedirect.com/science/article/pii/S221395672300186X |
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