Homosistein, Vitamin B12 and Folic Acid Levels in Patients with Pediatric Celiac Disease
Introduction: Our aim in this study was to investigate effects of vitamin B12 and folic acid malabsorption to homocysteine levels in celiac patients. Materials and Methods: Between 2-17 years of ages 32 celiac patients before treatment, 14 celiac patient in remission and 30 healthy controls involve...
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Galenos Publishing House
2015-04-01
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| Series: | Güncel Pediatri |
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| Online Access: | http://www.guncelpediatri.com/article_9981/Homosistein-Vitamin-B12-And-Folic-Acid-Levels-In-Patients-With-Pediatric-Celiac-Disease |
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| author | Dilek Beker Şanlı Yüksel Aliyazıcıoğlu Ayhan Gazi Kalaycı |
| author_facet | Dilek Beker Şanlı Yüksel Aliyazıcıoğlu Ayhan Gazi Kalaycı |
| author_sort | Dilek Beker Şanlı |
| collection | DOAJ |
| description | Introduction: Our aim in this study was to investigate effects of vitamin B12 and folic acid malabsorption to homocysteine levels in celiac patients.
Materials and Methods: Between 2-17 years of ages 32 celiac patients before treatment, 14 celiac patient in remission and 30 healthy controls involved in this study. Homocystein levels were evaluated in all groups. In addition plasma levels of vitamin B12 and folic acid determined in celiac and remission groups.
Results: Homocysteine levels as arithmetic mean±SD found 22.8±1.69 µmol/L in celiac group, 17.31±1.94 µmol/L in remission group and 15.21±1.69 µmol/L in control group. Folic acid levels as arithmetic mean±SD found 7.04±0.74 ng/ml in celiac patients and 12.95±1.9 ng/ml in remission group. There is statistically significant difference between folic acid and homocysteine levels of two groups (p<0.05). Vitamin B12 levels as arithmetic mean±SD found 433.31±70.91 pg/ml in celiac patients and 400.33±78.36 pg/ml in remission group. Difference between two groups is not statistically significant (p>0.05).
Conclusions: In our study homocysteine levels were found to be higher in celiac group than remission group. In this study, difference in folic acid levels between two groups may show that changes in folic acid levels related to changes in homocysteine levels. |
| format | Article |
| id | doaj-art-87d8d0eeb7bf469d8be1e20663252df3 |
| institution | Kabale University |
| issn | 1304-9054 |
| language | English |
| publishDate | 2015-04-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Güncel Pediatri |
| spelling | doaj-art-87d8d0eeb7bf469d8be1e20663252df32025-01-02T20:53:07ZengGalenos Publishing HouseGüncel Pediatri1304-90542015-04-011311610.4274/jcp.92400Homosistein, Vitamin B12 and Folic Acid Levels in Patients with Pediatric Celiac DiseaseDilek Beker Şanlı0Yüksel Aliyazıcıoğlu1Ayhan Gazi Kalaycı2Ümraniye Eğitim ve Araştırma Hastanesi, İstanbul, TürkiyeKaradeniz Teknik Üniversitesi Tıp Fakültesi, Biyokimya Anabilim Dalı Trabzon, TürkiyeOndokuz Mayıs Üniversitesi Tıp Fakültesi, Pediatrik Gastroenteroloji Anabilim Dalı, Samsun, TürkiyeIntroduction: Our aim in this study was to investigate effects of vitamin B12 and folic acid malabsorption to homocysteine levels in celiac patients. Materials and Methods: Between 2-17 years of ages 32 celiac patients before treatment, 14 celiac patient in remission and 30 healthy controls involved in this study. Homocystein levels were evaluated in all groups. In addition plasma levels of vitamin B12 and folic acid determined in celiac and remission groups. Results: Homocysteine levels as arithmetic mean±SD found 22.8±1.69 µmol/L in celiac group, 17.31±1.94 µmol/L in remission group and 15.21±1.69 µmol/L in control group. Folic acid levels as arithmetic mean±SD found 7.04±0.74 ng/ml in celiac patients and 12.95±1.9 ng/ml in remission group. There is statistically significant difference between folic acid and homocysteine levels of two groups (p<0.05). Vitamin B12 levels as arithmetic mean±SD found 433.31±70.91 pg/ml in celiac patients and 400.33±78.36 pg/ml in remission group. Difference between two groups is not statistically significant (p>0.05). Conclusions: In our study homocysteine levels were found to be higher in celiac group than remission group. In this study, difference in folic acid levels between two groups may show that changes in folic acid levels related to changes in homocysteine levels.http://www.guncelpediatri.com/article_9981/Homosistein-Vitamin-B12-And-Folic-Acid-Levels-In-Patients-With-Pediatric-Celiac-DiseaseCeliac diseasehomocysteinevitamin B12folic acid |
| spellingShingle | Dilek Beker Şanlı Yüksel Aliyazıcıoğlu Ayhan Gazi Kalaycı Homosistein, Vitamin B12 and Folic Acid Levels in Patients with Pediatric Celiac Disease Güncel Pediatri Celiac disease homocysteine vitamin B12 folic acid |
| title | Homosistein, Vitamin B12 and Folic Acid Levels in Patients with Pediatric Celiac Disease |
| title_full | Homosistein, Vitamin B12 and Folic Acid Levels in Patients with Pediatric Celiac Disease |
| title_fullStr | Homosistein, Vitamin B12 and Folic Acid Levels in Patients with Pediatric Celiac Disease |
| title_full_unstemmed | Homosistein, Vitamin B12 and Folic Acid Levels in Patients with Pediatric Celiac Disease |
| title_short | Homosistein, Vitamin B12 and Folic Acid Levels in Patients with Pediatric Celiac Disease |
| title_sort | homosistein vitamin b12 and folic acid levels in patients with pediatric celiac disease |
| topic | Celiac disease homocysteine vitamin B12 folic acid |
| url | http://www.guncelpediatri.com/article_9981/Homosistein-Vitamin-B12-And-Folic-Acid-Levels-In-Patients-With-Pediatric-Celiac-Disease |
| work_keys_str_mv | AT dilekbekersanlı homosisteinvitaminb12andfolicacidlevelsinpatientswithpediatricceliacdisease AT yukselaliyazıcıoglu homosisteinvitaminb12andfolicacidlevelsinpatientswithpediatricceliacdisease AT ayhangazikalaycı homosisteinvitaminb12andfolicacidlevelsinpatientswithpediatricceliacdisease |