Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake Cycles
The noise effects on a homeostatic regulation of sleep-wake cycles’ neuronal mathematical model determined by the hypocretin/orexin and the local glutamate interneurons spatiotemporal behaviors are studied within the neighborhood of stimulus threshold in this work; the neuronal noise added to the st...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Complexity |
| Online Access: | http://dx.doi.org/10.1155/2017/4797545 |
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| _version_ | 1850212126988173312 |
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| author | Wuyin Jin Qian Lin An Wang Chunni Wang |
| author_facet | Wuyin Jin Qian Lin An Wang Chunni Wang |
| author_sort | Wuyin Jin |
| collection | DOAJ |
| description | The noise effects on a homeostatic regulation of sleep-wake cycles’ neuronal mathematical model determined by the hypocretin/orexin and the local glutamate interneurons spatiotemporal behaviors are studied within the neighborhood of stimulus threshold in this work; the neuronal noise added to the stimulus, the conductance, and the activation variable of the modulation function are investigated, respectively, based on a circadian input skewed in sine function. The computer simulation results suggested that the increased amplitude of external current input will lead to the fact that awakening time is advanced but the sleepy time remains the same; for the bigger conductance and modulation noise, the regulatory mechanism of the model sometimes will be collapsed and the coupled two neurons of the model show very irregular activities; the falling asleep or wake transform appears at nondeterminate time. |
| format | Article |
| id | doaj-art-87d70c4de8124091975aac0bf5952ffa |
| institution | OA Journals |
| issn | 1076-2787 1099-0526 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Complexity |
| spelling | doaj-art-87d70c4de8124091975aac0bf5952ffa2025-08-20T02:09:24ZengWileyComplexity1076-27871099-05262017-01-01201710.1155/2017/47975454797545Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake CyclesWuyin Jin0Qian Lin1An Wang2Chunni Wang3School of Mechanical & Electronical Engineering, Lanzhou University of Technology, Lanzhou 730050, ChinaEditorial Department of Journal of Lanzhou University of Technology, Lanzhou University of Technology, Lanzhou 730050, ChinaSchool of Mechanical & Electronical Engineering, Lanzhou University of Technology, Lanzhou 730050, ChinaDepartment of Physics, Lanzhou University of Technology, Lanzhou 730050, ChinaThe noise effects on a homeostatic regulation of sleep-wake cycles’ neuronal mathematical model determined by the hypocretin/orexin and the local glutamate interneurons spatiotemporal behaviors are studied within the neighborhood of stimulus threshold in this work; the neuronal noise added to the stimulus, the conductance, and the activation variable of the modulation function are investigated, respectively, based on a circadian input skewed in sine function. The computer simulation results suggested that the increased amplitude of external current input will lead to the fact that awakening time is advanced but the sleepy time remains the same; for the bigger conductance and modulation noise, the regulatory mechanism of the model sometimes will be collapsed and the coupled two neurons of the model show very irregular activities; the falling asleep or wake transform appears at nondeterminate time.http://dx.doi.org/10.1155/2017/4797545 |
| spellingShingle | Wuyin Jin Qian Lin An Wang Chunni Wang Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake Cycles Complexity |
| title | Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake Cycles |
| title_full | Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake Cycles |
| title_fullStr | Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake Cycles |
| title_full_unstemmed | Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake Cycles |
| title_short | Computer Simulation of Noise Effects of the Neighborhood of Stimulus Threshold for a Mathematical Model of Homeostatic Regulation of Sleep-Wake Cycles |
| title_sort | computer simulation of noise effects of the neighborhood of stimulus threshold for a mathematical model of homeostatic regulation of sleep wake cycles |
| url | http://dx.doi.org/10.1155/2017/4797545 |
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