Neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders: a systematic scoping-review

Summary. Along with traditional research on psychiatric stigma, there has recently been increasing interest in the neurobiological factors associated with stigmatization.Aim: to study the most common research methods in the studies of the neurobiological correlates of stigmatization phenomenon and i...

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Main Authors: Natalia B. Lutova, Maria A. Khobeysh, Ekaterina S. Gerasimchuk, Maria O. Bocharova, Olga V. Makarevich, Mikhail Yu. Sorokin
Format: Article
Language:Russian
Published: Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation 2024-10-01
Series:Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
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Online Access:https://www.bekhterevreview.com/jour/article/view/1021
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author Natalia B. Lutova
Maria A. Khobeysh
Ekaterina S. Gerasimchuk
Maria O. Bocharova
Olga V. Makarevich
Mikhail Yu. Sorokin
author_facet Natalia B. Lutova
Maria A. Khobeysh
Ekaterina S. Gerasimchuk
Maria O. Bocharova
Olga V. Makarevich
Mikhail Yu. Sorokin
author_sort Natalia B. Lutova
collection DOAJ
description Summary. Along with traditional research on psychiatric stigma, there has recently been increasing interest in the neurobiological factors associated with stigmatization.Aim: to study the most common research methods in the studies of the neurobiological correlates of stigmatization phenomenon and its components, as well as to systematize their results, taking into account their methodological limitations.Materials and Methods: The review was conducted in accordance with the PRISMA-ScR extension. Studies were searched in MEDLINE, EMBASE, PsycINFO using the Ovid platform. After evaluating 2358 articles according to inclusion, non-inclusion, and exclusion criteria, 20 articles were included in the final analysis.Results: The most of the studies were conducted on samples of healthy respondents without a control group (14 articles). The mean age of respondents ranged from 18.8 [1.0] to 42.7 [14.7] years. Psychiatric stigma was studied in 2 studies; in the remaining articles, various components of stigma were studied, among which social rejection sensitivity was most often studied (13 articles). Among fMRI paradigm the Cyberball social exclusion task was used more often (10 articles). Changes in neural activity, correlating with the severity of stigma and its constituent constructs, were found in the anterior cingulate cortex, prefrontal cortex, insula, thalamus, hypothalamus, hippocampus, parahippocampal gyrus, ventral region of the striatum, putamen, amygdala.Conclusion: Functional magnetic resonance studies can be an effective tool for verifying and assessing the dynamics of the psychological state of people experiencing the phenomenon of stigmatization.
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institution Kabale University
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language Russian
publishDate 2024-10-01
publisher Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
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series Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
spelling doaj-art-87d6ab357d2c4e76807bb40bef647f712025-08-20T03:58:55ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2024-10-0158382510.31363/2313-7053-2024-880556Neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders: a systematic scoping-reviewNatalia B. Lutova0Maria A. Khobeysh1Ekaterina S. Gerasimchuk2Maria O. Bocharova3Olga V. Makarevich4Mikhail Yu. Sorokin5V.M. Bekhterev National Medical Research Center for Psychiatry and NeurologyV.M. Bekhterev National Medical Research Center for Psychiatry and NeurologyV.M. Bekhterev National Medical Research Center for Psychiatry and NeurologyV.M. Bekhterev National Medical Research Center for Psychiatry and Neurology; Institute of Psychiatry, Psychology & Neuroscience, King’s College LondonV.M. Bekhterev National Medical Research Center for Psychiatry and NeurologyV.M. Bekhterev National Medical Research Center for Psychiatry and NeurologySummary. Along with traditional research on psychiatric stigma, there has recently been increasing interest in the neurobiological factors associated with stigmatization.Aim: to study the most common research methods in the studies of the neurobiological correlates of stigmatization phenomenon and its components, as well as to systematize their results, taking into account their methodological limitations.Materials and Methods: The review was conducted in accordance with the PRISMA-ScR extension. Studies were searched in MEDLINE, EMBASE, PsycINFO using the Ovid platform. After evaluating 2358 articles according to inclusion, non-inclusion, and exclusion criteria, 20 articles were included in the final analysis.Results: The most of the studies were conducted on samples of healthy respondents without a control group (14 articles). The mean age of respondents ranged from 18.8 [1.0] to 42.7 [14.7] years. Psychiatric stigma was studied in 2 studies; in the remaining articles, various components of stigma were studied, among which social rejection sensitivity was most often studied (13 articles). Among fMRI paradigm the Cyberball social exclusion task was used more often (10 articles). Changes in neural activity, correlating with the severity of stigma and its constituent constructs, were found in the anterior cingulate cortex, prefrontal cortex, insula, thalamus, hypothalamus, hippocampus, parahippocampal gyrus, ventral region of the striatum, putamen, amygdala.Conclusion: Functional magnetic resonance studies can be an effective tool for verifying and assessing the dynamics of the psychological state of people experiencing the phenomenon of stigmatization.https://www.bekhterevreview.com/jour/article/view/1021stigmaself-stigmasocial rejectionneurosciencemental disordersfunctional neuroimagingmagnetic resonance imaging
spellingShingle Natalia B. Lutova
Maria A. Khobeysh
Ekaterina S. Gerasimchuk
Maria O. Bocharova
Olga V. Makarevich
Mikhail Yu. Sorokin
Neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders: a systematic scoping-review
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
stigma
self-stigma
social rejection
neuroscience
mental disorders
functional neuroimaging
magnetic resonance imaging
title Neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders: a systematic scoping-review
title_full Neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders: a systematic scoping-review
title_fullStr Neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders: a systematic scoping-review
title_full_unstemmed Neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders: a systematic scoping-review
title_short Neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders: a systematic scoping-review
title_sort neuroimaging markers of phenomena of perceived stigmatization in people with and without mental disorders a systematic scoping review
topic stigma
self-stigma
social rejection
neuroscience
mental disorders
functional neuroimaging
magnetic resonance imaging
url https://www.bekhterevreview.com/jour/article/view/1021
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