Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging Study

Purpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm’s canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with success...

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Main Authors: Livia M. Brandao, Andreas Schötzau, Matthias C. Grieshaber
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2015/457605
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author Livia M. Brandao
Andreas Schötzau
Matthias C. Grieshaber
author_facet Livia M. Brandao
Andreas Schötzau
Matthias C. Grieshaber
author_sort Livia M. Brandao
collection DOAJ
description Purpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm’s canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with successful positioning of the tensioning suture were included. The measurements were analyzed using linear mixed models, with the means adjusted to IOP, age, cup-to-disc ratio, and time of follow-up. Results. Mean follow-up time was 27.6 months (SD 10.5). Mean intraocular pressure (IOP) was 24.6 mmHg (SD 5.29), 13.8 (SD 2.65), and 14.5 (SD 0.71) before surgery, at 12 months, and at 36 months after surgery, respectively. 57.9% of patients had no medication at last evaluation. Differences and variations of measurements between the devices over a time of 12 months were not significant (p = 0.15 to 0.98). Some angles of distension associated with the suture stent inside SC were predictive for IOP reduction (p < 0.03 to < 0.001), but not for final IOP (p = 0.64 to 0.96). Conclusion. The angles of the inner wall of Schlemm’s canal generated by the suture stent were comparable between OCT and UBM and did not change significantly over time. There was a tendency towards a greater distension of Schlemm’s canal, when the difference was larger between pre- and postoperative IOP, suggesting the tensioning suture may contribute to IOP reduction.
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spelling doaj-art-87d66ab30a8444b8b5e8a129de6fe0912025-08-20T03:38:05ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/457605457605Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging StudyLivia M. Brandao0Andreas Schötzau1Matthias C. Grieshaber2Department of Ophthalmology, Glaucoma Service, University of Basel, Mittere Strasse 91, CH-4031 Basel, SwitzerlandDepartment of Ophthalmology, Glaucoma Service, University of Basel, Mittere Strasse 91, CH-4031 Basel, SwitzerlandDepartment of Ophthalmology, Glaucoma Service, University of Basel, Mittere Strasse 91, CH-4031 Basel, SwitzerlandPurpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm’s canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with successful positioning of the tensioning suture were included. The measurements were analyzed using linear mixed models, with the means adjusted to IOP, age, cup-to-disc ratio, and time of follow-up. Results. Mean follow-up time was 27.6 months (SD 10.5). Mean intraocular pressure (IOP) was 24.6 mmHg (SD 5.29), 13.8 (SD 2.65), and 14.5 (SD 0.71) before surgery, at 12 months, and at 36 months after surgery, respectively. 57.9% of patients had no medication at last evaluation. Differences and variations of measurements between the devices over a time of 12 months were not significant (p = 0.15 to 0.98). Some angles of distension associated with the suture stent inside SC were predictive for IOP reduction (p < 0.03 to < 0.001), but not for final IOP (p = 0.64 to 0.96). Conclusion. The angles of the inner wall of Schlemm’s canal generated by the suture stent were comparable between OCT and UBM and did not change significantly over time. There was a tendency towards a greater distension of Schlemm’s canal, when the difference was larger between pre- and postoperative IOP, suggesting the tensioning suture may contribute to IOP reduction.http://dx.doi.org/10.1155/2015/457605
spellingShingle Livia M. Brandao
Andreas Schötzau
Matthias C. Grieshaber
Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging Study
Journal of Ophthalmology
title Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging Study
title_full Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging Study
title_fullStr Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging Study
title_full_unstemmed Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging Study
title_short Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging Study
title_sort suture distension of schlemm s canal in canaloplasty an anterior segment imaging study
url http://dx.doi.org/10.1155/2015/457605
work_keys_str_mv AT liviambrandao suturedistensionofschlemmscanalincanaloplastyananteriorsegmentimagingstudy
AT andreasschotzau suturedistensionofschlemmscanalincanaloplastyananteriorsegmentimagingstudy
AT matthiascgrieshaber suturedistensionofschlemmscanalincanaloplastyananteriorsegmentimagingstudy