Identification of Coagulation and Fibrinolysis-Associated Biomarkers With Implications for Preeclampsia

Conclusion: Our bioinformatic analysis resulted in a diagnostic model (CYP19A1, C1QBP, GHR, and PSMA3) for PE related to coagulation and fibrinolysis. We also conducted immune microenvironment and drug sensitivity analyses, providing insights into PE diagnosis and treatment.

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Main Authors: Yujie Liu, Tingting Chen, Cuifang Fan
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Genetics Research
Online Access:http://dx.doi.org/10.1155/genr/6637484
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author Yujie Liu
Tingting Chen
Cuifang Fan
author_facet Yujie Liu
Tingting Chen
Cuifang Fan
author_sort Yujie Liu
collection DOAJ
description Conclusion: Our bioinformatic analysis resulted in a diagnostic model (CYP19A1, C1QBP, GHR, and PSMA3) for PE related to coagulation and fibrinolysis. We also conducted immune microenvironment and drug sensitivity analyses, providing insights into PE diagnosis and treatment.
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institution Kabale University
issn 1469-5073
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Genetics Research
spelling doaj-art-87d2a52b5b154fa9ad18e2b53fca7add2025-08-20T03:30:08ZengWileyGenetics Research1469-50732025-01-01202510.1155/genr/6637484Identification of Coagulation and Fibrinolysis-Associated Biomarkers With Implications for PreeclampsiaYujie Liu0Tingting Chen1Cuifang Fan2Department of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyConclusion: Our bioinformatic analysis resulted in a diagnostic model (CYP19A1, C1QBP, GHR, and PSMA3) for PE related to coagulation and fibrinolysis. We also conducted immune microenvironment and drug sensitivity analyses, providing insights into PE diagnosis and treatment.http://dx.doi.org/10.1155/genr/6637484
spellingShingle Yujie Liu
Tingting Chen
Cuifang Fan
Identification of Coagulation and Fibrinolysis-Associated Biomarkers With Implications for Preeclampsia
Genetics Research
title Identification of Coagulation and Fibrinolysis-Associated Biomarkers With Implications for Preeclampsia
title_full Identification of Coagulation and Fibrinolysis-Associated Biomarkers With Implications for Preeclampsia
title_fullStr Identification of Coagulation and Fibrinolysis-Associated Biomarkers With Implications for Preeclampsia
title_full_unstemmed Identification of Coagulation and Fibrinolysis-Associated Biomarkers With Implications for Preeclampsia
title_short Identification of Coagulation and Fibrinolysis-Associated Biomarkers With Implications for Preeclampsia
title_sort identification of coagulation and fibrinolysis associated biomarkers with implications for preeclampsia
url http://dx.doi.org/10.1155/genr/6637484
work_keys_str_mv AT yujieliu identificationofcoagulationandfibrinolysisassociatedbiomarkerswithimplicationsforpreeclampsia
AT tingtingchen identificationofcoagulationandfibrinolysisassociatedbiomarkerswithimplicationsforpreeclampsia
AT cuifangfan identificationofcoagulationandfibrinolysisassociatedbiomarkerswithimplicationsforpreeclampsia