Lactate in skin homeostasis: metabolism, skin barrier, and immunomodulation

Lactate in skin homeostasis: metabolism, skin barrier, and immunomodulation

Lactate, once considered merely a byproduct of glycolysis, is now increasingly recognized as a multifunctional signaling molecule with roles beyond energy metabolism. It functions as an enzyme cofactor and binds to specific receptors to modulate cellular functions. In the skin, lactate is produced b...

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Bibliographic Details
Main Authors: Dandan Ruan, Tingting Hu, Xuefan Yang, Xiaohui Mo, Qiang Ju
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
lactate
metabolism
skin barrier
immunomodulation
therapeutics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1510559/full
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