Surgical Site Infection Owing to Mycobacterium mageritense After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator Flap

Summary:. Mycobacterium mageritense is a rare, rapidly growing, nontuberculosis mycobacterium that belongs to type IV of the rapidly growing mycobacteria. These bacteria are found in soil and water, and cause localized skin and soft tissue infections; however, they are challenging to culture, leadin...

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Main Authors: Anna Suzuki, MD, Takako Komiya, MD, PhD, Hiroaki Fujita, MD, PhD, Kazuki Shimada, MD, PhD, Masahito Nonaka, MD, Mai Hanano, MD, Meisei Takeishi, MD, PhD, Takashi Ishikawa, MD, PhD, Hajime Matsumura, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2025-06-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006823
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author Anna Suzuki, MD
Takako Komiya, MD, PhD
Hiroaki Fujita, MD, PhD
Kazuki Shimada, MD, PhD
Masahito Nonaka, MD
Mai Hanano, MD
Meisei Takeishi, MD, PhD
Takashi Ishikawa, MD, PhD
Hajime Matsumura, MD, PhD
author_facet Anna Suzuki, MD
Takako Komiya, MD, PhD
Hiroaki Fujita, MD, PhD
Kazuki Shimada, MD, PhD
Masahito Nonaka, MD
Mai Hanano, MD
Meisei Takeishi, MD, PhD
Takashi Ishikawa, MD, PhD
Hajime Matsumura, MD, PhD
author_sort Anna Suzuki, MD
collection DOAJ
description Summary:. Mycobacterium mageritense is a rare, rapidly growing, nontuberculosis mycobacterium that belongs to type IV of the rapidly growing mycobacteria. These bacteria are found in soil and water, and cause localized skin and soft tissue infections; however, they are challenging to culture, leading to diagnostic delays. To our knowledge, there have been 12 reported cases of surgical site infections (SSIs) caused by M. mageritense, with only 2 cases following breast reconstruction. A 51-year-old woman underwent nipple-sparing mastectomy and immediate breast reconstruction using a deep inferior epigastric perforator flap for invasive ductal carcinoma of the left breast. One month after surgery, she developed an SSI caused by M. mageritense. Despite initial outpatient treatment, the infection persisted, requiring multiple hospitalizations, administration of intravenous antibiotics, and several debridements under general anesthesia. Negative pressure wound therapy and a coordinated approach among various medical specialties are essential for managing infections. The patient experienced side effects from prolonged antibiotic use but eventually exhibited no signs of infection recurrence. This case highlights the challenges in diagnosing and treating M. mageritense SSIs, emphasizing the need for comprehensive surgical and medical management, together with patient-centered care, to effectively manage long-term treatment.
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spelling doaj-art-87c9fcdef267403cabc3b81ae79a11122025-08-20T02:10:28ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742025-06-01136e682310.1097/GOX.0000000000006823202506000-00010Surgical Site Infection Owing to Mycobacterium mageritense After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator FlapAnna Suzuki, MD0Takako Komiya, MD, PhD1Hiroaki Fujita, MD, PhD2Kazuki Shimada, MD, PhD3Masahito Nonaka, MD4Mai Hanano, MD5Meisei Takeishi, MD, PhD6Takashi Ishikawa, MD, PhD7Hajime Matsumura, MD, PhD8From the * Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, JapanFrom the * Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, Japan† Department of Infection Prevention and Control, Tokyo Medical University, Tokyo, JapanFrom the * Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, JapanFrom the * Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, JapanFrom the * Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, JapanFrom the * Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, Japan‡ Department of Breast Surgery, Tokyo Medical University, Tokyo, Japan.From the * Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, JapanSummary:. Mycobacterium mageritense is a rare, rapidly growing, nontuberculosis mycobacterium that belongs to type IV of the rapidly growing mycobacteria. These bacteria are found in soil and water, and cause localized skin and soft tissue infections; however, they are challenging to culture, leading to diagnostic delays. To our knowledge, there have been 12 reported cases of surgical site infections (SSIs) caused by M. mageritense, with only 2 cases following breast reconstruction. A 51-year-old woman underwent nipple-sparing mastectomy and immediate breast reconstruction using a deep inferior epigastric perforator flap for invasive ductal carcinoma of the left breast. One month after surgery, she developed an SSI caused by M. mageritense. Despite initial outpatient treatment, the infection persisted, requiring multiple hospitalizations, administration of intravenous antibiotics, and several debridements under general anesthesia. Negative pressure wound therapy and a coordinated approach among various medical specialties are essential for managing infections. The patient experienced side effects from prolonged antibiotic use but eventually exhibited no signs of infection recurrence. This case highlights the challenges in diagnosing and treating M. mageritense SSIs, emphasizing the need for comprehensive surgical and medical management, together with patient-centered care, to effectively manage long-term treatment.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006823
spellingShingle Anna Suzuki, MD
Takako Komiya, MD, PhD
Hiroaki Fujita, MD, PhD
Kazuki Shimada, MD, PhD
Masahito Nonaka, MD
Mai Hanano, MD
Meisei Takeishi, MD, PhD
Takashi Ishikawa, MD, PhD
Hajime Matsumura, MD, PhD
Surgical Site Infection Owing to Mycobacterium mageritense After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator Flap
Plastic and Reconstructive Surgery, Global Open
title Surgical Site Infection Owing to Mycobacterium mageritense After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator Flap
title_full Surgical Site Infection Owing to Mycobacterium mageritense After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator Flap
title_fullStr Surgical Site Infection Owing to Mycobacterium mageritense After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator Flap
title_full_unstemmed Surgical Site Infection Owing to Mycobacterium mageritense After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator Flap
title_short Surgical Site Infection Owing to Mycobacterium mageritense After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator Flap
title_sort surgical site infection owing to mycobacterium mageritense after immediate breast reconstruction using a deep inferior epigastric perforator flap
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006823
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