Alteration of the microRNA network during the progression of Alzheimer's disease

Alteration of the microRNA network during the progression of Alzheimer's disease

Abstract An overview of miRNAs altered in Alzheimer's disease (AD) was established by profiling the hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing deregulation of 35 miRNAs. Profiling of miRNAs in the prefrontal cortex of a second independent cohort of 49 p...

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Main Authors: Pierre Lau, Koen Bossers, Rekin's Janky, Evgenia Salta, Carlo Sala Frigerio, Shahar Barbash, Roy Rothman, Annerieke S. R. Sierksma, Amantha Thathiah, David Greenberg, Aikaterini S. Papadopoulou, Tilmann Achsel, Torik Ayoubi, Hermona Soreq, Joost Verhaagen, Dick F. Swaab, Stein Aerts, Bart De Strooper
Format: Article
Language:English
Published: Springer Nature 2013-09-01
Series:EMBO Molecular Medicine
Subjects:
Alzheimer's disease
hippocampus
prefrontal cortex
microRNA
miR‐132‐3p
Online Access:https://doi.org/10.1002/emmm.201201974
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