Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends
Primary hyperparathyroidism (PHPT) has become an asymptomatic disease in the Western world with the introduction of routine calcium screening. However, the same phenomenon is not observed in India. We have now systematically reviewed the status of PHPT in India. While there is a paucity of literatur...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2011/921814 |
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| author | P. V. Pradeep B. Jayashree Anjali Mishra S. K. Mishra |
| author_facet | P. V. Pradeep B. Jayashree Anjali Mishra S. K. Mishra |
| author_sort | P. V. Pradeep |
| collection | DOAJ |
| description | Primary hyperparathyroidism (PHPT) has become an asymptomatic disease in the Western world with the introduction of routine calcium screening. However, the same phenomenon is not observed in India. We have now systematically reviewed the status of PHPT in India. While there is a paucity of literature on PHPT from India when compared to Western countries, some information can be gleaned upon. Most patients present with symptomatic disease whereas very few are screen-detected cases (bone disease 77%, renal disease 36%, and 5.6% asymptomatic). Mean calcium, parathyroid hormone (PTH), and alkaline phosphate levels are high while Vitamin D levels are low. The average parathyroid gland weight is large and the majority being parathyroid adenomas (89.1%). Hungry bone syndrome (HBS) is common in the postoperative period. The disease-related mortality rate is 7.4%, recurrence 4.16%, and persistent disease 2.17%. We suggest that dedicated efforts are needed to pick up asymptomatic disease in India by methods like incorporating calcium estimation in the routine health check-up programs. |
| format | Article |
| id | doaj-art-87bb1f3814774156b54ee8b3c4aa287b |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-87bb1f3814774156b54ee8b3c4aa287b2025-02-03T01:03:30ZengWileyInternational Journal of Endocrinology1687-83371687-83452011-01-01201110.1155/2011/921814921814Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future TrendsP. V. Pradeep0B. Jayashree1Anjali Mishra2S. K. Mishra3Narayana Medical College and Superspeciality Hospitals, Nellore, Andhra Pradesh, IndiaNarayana Medical College and Superspeciality Hospitals, Nellore, Andhra Pradesh, IndiaSanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, IndiaSanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, IndiaPrimary hyperparathyroidism (PHPT) has become an asymptomatic disease in the Western world with the introduction of routine calcium screening. However, the same phenomenon is not observed in India. We have now systematically reviewed the status of PHPT in India. While there is a paucity of literature on PHPT from India when compared to Western countries, some information can be gleaned upon. Most patients present with symptomatic disease whereas very few are screen-detected cases (bone disease 77%, renal disease 36%, and 5.6% asymptomatic). Mean calcium, parathyroid hormone (PTH), and alkaline phosphate levels are high while Vitamin D levels are low. The average parathyroid gland weight is large and the majority being parathyroid adenomas (89.1%). Hungry bone syndrome (HBS) is common in the postoperative period. The disease-related mortality rate is 7.4%, recurrence 4.16%, and persistent disease 2.17%. We suggest that dedicated efforts are needed to pick up asymptomatic disease in India by methods like incorporating calcium estimation in the routine health check-up programs.http://dx.doi.org/10.1155/2011/921814 |
| spellingShingle | P. V. Pradeep B. Jayashree Anjali Mishra S. K. Mishra Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends International Journal of Endocrinology |
| title | Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends |
| title_full | Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends |
| title_fullStr | Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends |
| title_full_unstemmed | Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends |
| title_short | Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends |
| title_sort | systematic review of primary hyperparathyroidism in india the past present and the future trends |
| url | http://dx.doi.org/10.1155/2011/921814 |
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