Effect and toxicity of PF chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer: Medical thermography test

Cancer is one of the leading causes of death worldwide, and treatment options and prognosis for patients with advanced cancer are particularly challenging. PF chemotherapy regimen (the combination of cisplatin and 5-fluorouracil) has been widely used in the treatment of a variety of cancers, and rad...

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Main Authors: Caixia Gou, Wang Qi, Pengbing Han, Chunlin Zhang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:SLAS Technology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2472630325000858
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author Caixia Gou
Wang Qi
Pengbing Han
Chunlin Zhang
author_facet Caixia Gou
Wang Qi
Pengbing Han
Chunlin Zhang
author_sort Caixia Gou
collection DOAJ
description Cancer is one of the leading causes of death worldwide, and treatment options and prognosis for patients with advanced cancer are particularly challenging. PF chemotherapy regimen (the combination of cisplatin and 5-fluorouracil) has been widely used in the treatment of a variety of cancers, and radiotherapy as a local treatment can effectively control tumor growth. This is a prospective clinical trial in which patients were treated with PF chemotherapy combined with radiotherapy. Medical thermal imaging was performed on all patients before, during and after treatment. The examination process involves recording the patient's body surface temperature using a highly sensitive infrared camera and analyzing temperature changes in the tumor area and surrounding tissue. Clinical data on patients were also collected, including treatment response, quality of life scores, and reports of toxic and side effects. Preliminary results showed that PF chemotherapy combined with radiotherapy showed a positive effect in controlling tumor growth, and most patients experienced a reduction in tumor volume. Medical thermal image examination revealed significant changes in tumor area temperature during treatment, which correlated with tumor reactivity. In some cases, thermal imagery shows potential skin and mucosal damage in advance, suggesting the need for early intervention. Thermal imagery also helped assess the impact of treatment on patients' quality of life, such as pain and discomfort by looking at changes in the patient's body surface temperature distribution.
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spelling doaj-art-87ad039d3f384e3db3b0affdfee8661d2025-08-20T04:00:27ZengElsevierSLAS Technology2472-63032025-08-013310032710.1016/j.slast.2025.100327Effect and toxicity of PF chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer: Medical thermography testCaixia Gou0Wang Qi1Pengbing Han2Chunlin Zhang3Department of Radiotherapy, Gansu Tumor Hospital, Lanzhou 730050, Gansu Province, ChinaDepartment of Gynecologic Tumor, Gansu Tumor Hospital, Lanzhou 730050, Gansu Province, ChinaDepartment of Gynecologic Tumor, Gansu Tumor Hospital, Lanzhou 730050, Gansu Province, ChinaDepartment of Radiotherapy, Gansu Tumor Hospital, Lanzhou 730050, Gansu Province, China; Corresponding author.Cancer is one of the leading causes of death worldwide, and treatment options and prognosis for patients with advanced cancer are particularly challenging. PF chemotherapy regimen (the combination of cisplatin and 5-fluorouracil) has been widely used in the treatment of a variety of cancers, and radiotherapy as a local treatment can effectively control tumor growth. This is a prospective clinical trial in which patients were treated with PF chemotherapy combined with radiotherapy. Medical thermal imaging was performed on all patients before, during and after treatment. The examination process involves recording the patient's body surface temperature using a highly sensitive infrared camera and analyzing temperature changes in the tumor area and surrounding tissue. Clinical data on patients were also collected, including treatment response, quality of life scores, and reports of toxic and side effects. Preliminary results showed that PF chemotherapy combined with radiotherapy showed a positive effect in controlling tumor growth, and most patients experienced a reduction in tumor volume. Medical thermal image examination revealed significant changes in tumor area temperature during treatment, which correlated with tumor reactivity. In some cases, thermal imagery shows potential skin and mucosal damage in advance, suggesting the need for early intervention. Thermal imagery also helped assess the impact of treatment on patients' quality of life, such as pain and discomfort by looking at changes in the patient's body surface temperature distribution.http://www.sciencedirect.com/science/article/pii/S2472630325000858Pf chemotherapyRadiotherapyAdvanced cancerCurative effect analysisToxic and side effectsMedical thermal imaging
spellingShingle Caixia Gou
Wang Qi
Pengbing Han
Chunlin Zhang
Effect and toxicity of PF chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer: Medical thermography test
SLAS Technology
Pf chemotherapy
Radiotherapy
Advanced cancer
Curative effect analysis
Toxic and side effects
Medical thermal imaging
title Effect and toxicity of PF chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer: Medical thermography test
title_full Effect and toxicity of PF chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer: Medical thermography test
title_fullStr Effect and toxicity of PF chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer: Medical thermography test
title_full_unstemmed Effect and toxicity of PF chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer: Medical thermography test
title_short Effect and toxicity of PF chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer: Medical thermography test
title_sort effect and toxicity of pf chemotherapy combined with radiotherapy in the treatment of advanced cervical cancer medical thermography test
topic Pf chemotherapy
Radiotherapy
Advanced cancer
Curative effect analysis
Toxic and side effects
Medical thermal imaging
url http://www.sciencedirect.com/science/article/pii/S2472630325000858
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AT pengbinghan effectandtoxicityofpfchemotherapycombinedwithradiotherapyinthetreatmentofadvancedcervicalcancermedicalthermographytest
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