Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's disease
Key Clinical Message Castleman's Disease should be considered in the differential diagnosis of retroperitoneal masses, especially in equivocal cases. Clinician should not presume all cases of retroperitoneal masses as a malignancy. Abstract Castleman's Disease is a heterogeneous group of l...
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Wiley
2024-09-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.9451 |
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| author | Engy S. Alhariry Abdulkarim Hasan Ashraf Abdelghany Khalid Nafie |
| author_facet | Engy S. Alhariry Abdulkarim Hasan Ashraf Abdelghany Khalid Nafie |
| author_sort | Engy S. Alhariry |
| collection | DOAJ |
| description | Key Clinical Message Castleman's Disease should be considered in the differential diagnosis of retroperitoneal masses, especially in equivocal cases. Clinician should not presume all cases of retroperitoneal masses as a malignancy. Abstract Castleman's Disease is a heterogeneous group of lymphoproliferative disorders, that can develop in lymph nodes or in extranodal sites. It has three distinct histological subtypes; hyaline vascular, plasma cell or mixed. It can be unicentric or multicentric, and sometimes oligocentric or regional. In this article, we report a case of a 30‐year‐old male who presented with a palpable left lumbar mass, clinically suspected as sarcoma vs GIST, which was surgically excised and pathologically examined revealing a rare condition of intra‐abdominal unicentric Castleman's Disease with good prognosis. Castleman's Disease should be considered in the differential diagnosis of retroperitoneal masses, especially in equivocal cases. |
| format | Article |
| id | doaj-art-87a8833f235b410db80d72cffc2c943f |
| institution | OA Journals |
| issn | 2050-0904 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-87a8833f235b410db80d72cffc2c943f2025-08-20T01:59:05ZengWileyClinical Case Reports2050-09042024-09-01129n/an/a10.1002/ccr3.9451Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's diseaseEngy S. Alhariry0Abdulkarim Hasan1Ashraf Abdelghany2Khalid Nafie3Pathology Department Shefaa Al Orman Hospital Luxor EgyptFaculty of Medicine Al‐Azhar University Cairo EgyptFaculty of Medicine Al‐Azhar University Cairo EgyptPathology and Laboratory Medicine Ministry of Health Khartoum SudanKey Clinical Message Castleman's Disease should be considered in the differential diagnosis of retroperitoneal masses, especially in equivocal cases. Clinician should not presume all cases of retroperitoneal masses as a malignancy. Abstract Castleman's Disease is a heterogeneous group of lymphoproliferative disorders, that can develop in lymph nodes or in extranodal sites. It has three distinct histological subtypes; hyaline vascular, plasma cell or mixed. It can be unicentric or multicentric, and sometimes oligocentric or regional. In this article, we report a case of a 30‐year‐old male who presented with a palpable left lumbar mass, clinically suspected as sarcoma vs GIST, which was surgically excised and pathologically examined revealing a rare condition of intra‐abdominal unicentric Castleman's Disease with good prognosis. Castleman's Disease should be considered in the differential diagnosis of retroperitoneal masses, especially in equivocal cases.https://doi.org/10.1002/ccr3.9451Castleman's diseasehistopathologyimmunohistochemistryretroperitoneal mass |
| spellingShingle | Engy S. Alhariry Abdulkarim Hasan Ashraf Abdelghany Khalid Nafie Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's disease Clinical Case Reports Castleman's disease histopathology immunohistochemistry retroperitoneal mass |
| title | Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's disease |
| title_full | Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's disease |
| title_fullStr | Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's disease |
| title_full_unstemmed | Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's disease |
| title_short | Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's disease |
| title_sort | localized retroperitoneal mass suspected malignancy a rare case of unicentric castleman s disease |
| topic | Castleman's disease histopathology immunohistochemistry retroperitoneal mass |
| url | https://doi.org/10.1002/ccr3.9451 |
| work_keys_str_mv | AT engysalhariry localizedretroperitonealmasssuspectedmalignancyararecaseofunicentriccastlemansdisease AT abdulkarimhasan localizedretroperitonealmasssuspectedmalignancyararecaseofunicentriccastlemansdisease AT ashrafabdelghany localizedretroperitonealmasssuspectedmalignancyararecaseofunicentriccastlemansdisease AT khalidnafie localizedretroperitonealmasssuspectedmalignancyararecaseofunicentriccastlemansdisease |