A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer
Abstract Background Long non-coding RNAs (lncRNAs) play crucial roles in cancer pathogenesis, including colorectal cancer (CRC). Distinct lncRNA transcripts from the same gene show diverse regulatory roles in cancer. The MIR100HG, a lncRNA gene characterized by multiple transcript variants, has been...
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| Main Authors: | Mingrui Dai, Yuhua Shi, Hailin Zhao, Yue Hu, Xianling Cong, Bin Yu, Haihong Zhang, Xianghui Yu, Hui Wu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Cell Communication and Signaling |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12964-025-02280-2 |
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