Analysis of Genotypes and Phenotypes in Chinese Patients With Tuberous Sclerosis Complex Harboring Novel Variants of TSC1 and TSC2 Genes

Conclusions: This study broadens the spectrum of variants of TSC1 and TSC2 genes, reaffirming the clinical diagnosis of patients through genetic testing.

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Main Authors: Jian Chen, Hairui Sun, Ling Han, Xiaoyan Gu, Xiaoyan Hao, Yuwei Fu, Zongjie Weng, Yi Xiong, Baomin Liu, Hongjia Zhang, Yihua He, Hong Li
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/ijog/6963280
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author Jian Chen
Hairui Sun
Ling Han
Xiaoyan Gu
Xiaoyan Hao
Yuwei Fu
Zongjie Weng
Yi Xiong
Baomin Liu
Hongjia Zhang
Yihua He
Hong Li
author_facet Jian Chen
Hairui Sun
Ling Han
Xiaoyan Gu
Xiaoyan Hao
Yuwei Fu
Zongjie Weng
Yi Xiong
Baomin Liu
Hongjia Zhang
Yihua He
Hong Li
author_sort Jian Chen
collection DOAJ
description Conclusions: This study broadens the spectrum of variants of TSC1 and TSC2 genes, reaffirming the clinical diagnosis of patients through genetic testing.
format Article
id doaj-art-87a650acf1f94c9cad9dc41d2a0133a5
institution Kabale University
issn 2314-4378
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series International Journal of Genomics
spelling doaj-art-87a650acf1f94c9cad9dc41d2a0133a52025-08-20T03:49:41ZengWileyInternational Journal of Genomics2314-43782025-01-01202510.1155/ijog/6963280Analysis of Genotypes and Phenotypes in Chinese Patients With Tuberous Sclerosis Complex Harboring Novel Variants of TSC1 and TSC2 GenesJian Chen0Hairui Sun1Ling Han2Xiaoyan Gu3Xiaoyan Hao4Yuwei Fu5Zongjie Weng6Yi Xiong7Baomin Liu8Hongjia Zhang9Yihua He10Hong Li11Department of EchocardiographyMaternal-Fetal Consultation Center of Congenital Heart DiseaseMaternal-Fetal Consultation Center of Congenital Heart DiseaseMaternal-Fetal Consultation Center of Congenital Heart DiseaseMaternal-Fetal Consultation Center of Congenital Heart DiseaseMaternal-Fetal Consultation Center of Congenital Heart DiseaseDepartment of UltrasonographyDepartment of UltrasonographyDepartment of UltrasonographyDepartment of Cardiac SurgeryMaternal-Fetal Consultation Center of Congenital Heart DiseaseDepartment of UltrasoundConclusions: This study broadens the spectrum of variants of TSC1 and TSC2 genes, reaffirming the clinical diagnosis of patients through genetic testing.http://dx.doi.org/10.1155/ijog/6963280
spellingShingle Jian Chen
Hairui Sun
Ling Han
Xiaoyan Gu
Xiaoyan Hao
Yuwei Fu
Zongjie Weng
Yi Xiong
Baomin Liu
Hongjia Zhang
Yihua He
Hong Li
Analysis of Genotypes and Phenotypes in Chinese Patients With Tuberous Sclerosis Complex Harboring Novel Variants of TSC1 and TSC2 Genes
International Journal of Genomics
title Analysis of Genotypes and Phenotypes in Chinese Patients With Tuberous Sclerosis Complex Harboring Novel Variants of TSC1 and TSC2 Genes
title_full Analysis of Genotypes and Phenotypes in Chinese Patients With Tuberous Sclerosis Complex Harboring Novel Variants of TSC1 and TSC2 Genes
title_fullStr Analysis of Genotypes and Phenotypes in Chinese Patients With Tuberous Sclerosis Complex Harboring Novel Variants of TSC1 and TSC2 Genes
title_full_unstemmed Analysis of Genotypes and Phenotypes in Chinese Patients With Tuberous Sclerosis Complex Harboring Novel Variants of TSC1 and TSC2 Genes
title_short Analysis of Genotypes and Phenotypes in Chinese Patients With Tuberous Sclerosis Complex Harboring Novel Variants of TSC1 and TSC2 Genes
title_sort analysis of genotypes and phenotypes in chinese patients with tuberous sclerosis complex harboring novel variants of tsc1 and tsc2 genes
url http://dx.doi.org/10.1155/ijog/6963280
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