Seeding Stress Resilience through Inoculation
Stress is a generalized set of physiological and psychological responses observed when an organism is placed under challenging circumstances. The stress response allows organisms to reattain the equilibrium in face of perturbations. Unfortunately, chronic and/or traumatic exposure to stress frequent...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2016/4928081 |
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| _version_ | 1832551745433108480 |
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| author | Archana Ashokan Meenalochani Sivasubramanian Rupshi Mitra |
| author_facet | Archana Ashokan Meenalochani Sivasubramanian Rupshi Mitra |
| author_sort | Archana Ashokan |
| collection | DOAJ |
| description | Stress is a generalized set of physiological and psychological responses observed when an organism is placed under challenging circumstances. The stress response allows organisms to reattain the equilibrium in face of perturbations. Unfortunately, chronic and/or traumatic exposure to stress frequently overwhelms coping ability of an individual. This is manifested as symptoms affecting emotions and cognition in stress-related mental disorders. Thus environmental interventions that promote resilience in face of stress have much clinical relevance. Focus of the bulk of relevant neurobiological research at present remains on negative aspects of health and psychological outcomes of stress exposure. Yet exposure to the stress itself can promote resilience to subsequent stressful episodes later in the life. This is especially true if the prior stress occurs early in life, is mild in its magnitude, and is controllable by the individual. This articulation has been referred to as “stress inoculation,” reminiscent of resilience to the pathology generated through vaccination by attenuated pathogen itself. Using experimental evidence from animal models, this review explores relationship between nature of the “inoculum” stress and subsequent psychological resilience. |
| format | Article |
| id | doaj-art-87a1ad8625a64ee59809742099abb788 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-87a1ad8625a64ee59809742099abb7882025-02-03T06:00:44ZengWileyNeural Plasticity2090-59041687-54432016-01-01201610.1155/2016/49280814928081Seeding Stress Resilience through InoculationArchana Ashokan0Meenalochani Sivasubramanian1Rupshi Mitra2School of Biological Sciences, Nanyang Technological University, 637551, SingaporeSchool of Biological Sciences, Nanyang Technological University, 637551, SingaporeSchool of Biological Sciences, Nanyang Technological University, 637551, SingaporeStress is a generalized set of physiological and psychological responses observed when an organism is placed under challenging circumstances. The stress response allows organisms to reattain the equilibrium in face of perturbations. Unfortunately, chronic and/or traumatic exposure to stress frequently overwhelms coping ability of an individual. This is manifested as symptoms affecting emotions and cognition in stress-related mental disorders. Thus environmental interventions that promote resilience in face of stress have much clinical relevance. Focus of the bulk of relevant neurobiological research at present remains on negative aspects of health and psychological outcomes of stress exposure. Yet exposure to the stress itself can promote resilience to subsequent stressful episodes later in the life. This is especially true if the prior stress occurs early in life, is mild in its magnitude, and is controllable by the individual. This articulation has been referred to as “stress inoculation,” reminiscent of resilience to the pathology generated through vaccination by attenuated pathogen itself. Using experimental evidence from animal models, this review explores relationship between nature of the “inoculum” stress and subsequent psychological resilience.http://dx.doi.org/10.1155/2016/4928081 |
| spellingShingle | Archana Ashokan Meenalochani Sivasubramanian Rupshi Mitra Seeding Stress Resilience through Inoculation Neural Plasticity |
| title | Seeding Stress Resilience through Inoculation |
| title_full | Seeding Stress Resilience through Inoculation |
| title_fullStr | Seeding Stress Resilience through Inoculation |
| title_full_unstemmed | Seeding Stress Resilience through Inoculation |
| title_short | Seeding Stress Resilience through Inoculation |
| title_sort | seeding stress resilience through inoculation |
| url | http://dx.doi.org/10.1155/2016/4928081 |
| work_keys_str_mv | AT archanaashokan seedingstressresiliencethroughinoculation AT meenalochanisivasubramanian seedingstressresiliencethroughinoculation AT rupshimitra seedingstressresiliencethroughinoculation |