Systemic inflammation as a central player in the initiation and development of Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is an age-related neurodegenerative disorder and the most common cause of dementia. While the amyloid cascade hypothesis has long dominated AD research, emerging evidence suggests that neuroinflammation may play a more central role in disease onset and progression....

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Bibliographic Details
Main Authors: Irem Bayraktaroglu, Natalia Ortí-Casañ, Debby Van Dam, Peter P. De Deyn, Ulrich L. M. Eisel
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Immunity & Ageing
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Online Access:https://doi.org/10.1186/s12979-025-00529-5
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