MXenes as emerging materials to repair electroactive tissues and organs
Nanomaterials with electroactive properties have taken a big leap for tissue repair and regeneration due to their unique physiochemical properties and biocompatibility. MXenes, an emerging class of electroactive materials have generated considerable interest for their biomedical applications from be...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2025-06-01
|
| Series: | Bioactive Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X2500043X |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850201008667361280 |
|---|---|
| author | Keshav Narayan Alagarsamy Leena Regi Saleth Saravanan Sekaran Laura Fusco Lucia Gemma Delogu Maksym Pogorielov Açelya Yilmazer Sanjiv Dhingra |
| author_facet | Keshav Narayan Alagarsamy Leena Regi Saleth Saravanan Sekaran Laura Fusco Lucia Gemma Delogu Maksym Pogorielov Açelya Yilmazer Sanjiv Dhingra |
| author_sort | Keshav Narayan Alagarsamy |
| collection | DOAJ |
| description | Nanomaterials with electroactive properties have taken a big leap for tissue repair and regeneration due to their unique physiochemical properties and biocompatibility. MXenes, an emerging class of electroactive materials have generated considerable interest for their biomedical applications from bench to bedside. Recently, the application of these two-dimensional wonder materials have been extensively investigated in the areas of biosensors, bioimaging and repair of electroactive organs, owing to their outstanding electromechanical properties, photothermal capabilities, hydrophilicity, and flexibility. The currently available data reports that there is significant potential to employ MXene nanomaterials for repair, regeneration and functioning of electroactive tissues and organs such as brain, spinal cord, heart, bone, skeletal muscle and skin. The current review is the first report that compiles the most recent advances in the application of MXenes in bioelectronics and the development of biomimetic scaffolds for repair, regeneration and functioning of electroactive tissues and organs including heart, nervous system, skin, bone and skeletal muscle. The content in this article focuses on unique features of MXenes, synthesis process, with emphasis on MXene-based electroactive tissue engineering constructs, biosensors and wearable biointerfaces. Additionally, a section on the future of MXenes is presented with a focus on the clinical applications of MXenes. |
| format | Article |
| id | doaj-art-8792cb36c8a74cbfa07a6c3d7864b934 |
| institution | OA Journals |
| issn | 2452-199X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj-art-8792cb36c8a74cbfa07a6c3d7864b9342025-08-20T02:12:10ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2025-06-014858360810.1016/j.bioactmat.2025.01.035MXenes as emerging materials to repair electroactive tissues and organsKeshav Narayan Alagarsamy0Leena Regi Saleth1Saravanan Sekaran2Laura Fusco3Lucia Gemma Delogu4Maksym Pogorielov5Açelya Yilmazer6Sanjiv Dhingra7Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, Biomedical Engineering Program, University of Manitoba, Winnipeg, Manitoba, R2H 2A6, CanadaInstitute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, Biomedical Engineering Program, University of Manitoba, Winnipeg, Manitoba, R2H 2A6, CanadaDepartment of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute for Medical and Technical Sciences, Saveetha University, Chennai, 600077, Tamil Nadu, IndiaUniversity of Science & Technology, Abu Dhabi, United Arab Emirates; ImmuneNano-Lab, Department of Biomedical Sciences, University of Padua, Padua, ItalyUniversity of Science & Technology, Abu Dhabi, United Arab Emirates; ImmuneNano-Lab, Department of Biomedical Sciences, University of Padua, Padua, ItalySumy State University, 2 Rymskogo-Korsakova Street, Sumy, 40007, Ukraine; University of Latvia, 3 Jelgavas Street, Riga, LV-1004, LatviaDepartment of Biomedical Engineering, Ankara University, Golbasi, Ankara, 06830, Turkey; Stem Cell Institute, Ankara University, Balgat, Ankara, 06520, TurkeyInstitute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, Biomedical Engineering Program, University of Manitoba, Winnipeg, Manitoba, R2H 2A6, Canada; Corresponding author. Biomedical Engineering Program , Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre , University of Manitoba, R-3028-2, 351 Tache Avenue, Winnipeg, R2H2A6, Canada.Nanomaterials with electroactive properties have taken a big leap for tissue repair and regeneration due to their unique physiochemical properties and biocompatibility. MXenes, an emerging class of electroactive materials have generated considerable interest for their biomedical applications from bench to bedside. Recently, the application of these two-dimensional wonder materials have been extensively investigated in the areas of biosensors, bioimaging and repair of electroactive organs, owing to their outstanding electromechanical properties, photothermal capabilities, hydrophilicity, and flexibility. The currently available data reports that there is significant potential to employ MXene nanomaterials for repair, regeneration and functioning of electroactive tissues and organs such as brain, spinal cord, heart, bone, skeletal muscle and skin. The current review is the first report that compiles the most recent advances in the application of MXenes in bioelectronics and the development of biomimetic scaffolds for repair, regeneration and functioning of electroactive tissues and organs including heart, nervous system, skin, bone and skeletal muscle. The content in this article focuses on unique features of MXenes, synthesis process, with emphasis on MXene-based electroactive tissue engineering constructs, biosensors and wearable biointerfaces. Additionally, a section on the future of MXenes is presented with a focus on the clinical applications of MXenes.http://www.sciencedirect.com/science/article/pii/S2452199X2500043XMXenesBiosensorsTissue engineeringElectroactive |
| spellingShingle | Keshav Narayan Alagarsamy Leena Regi Saleth Saravanan Sekaran Laura Fusco Lucia Gemma Delogu Maksym Pogorielov Açelya Yilmazer Sanjiv Dhingra MXenes as emerging materials to repair electroactive tissues and organs Bioactive Materials MXenes Biosensors Tissue engineering Electroactive |
| title | MXenes as emerging materials to repair electroactive tissues and organs |
| title_full | MXenes as emerging materials to repair electroactive tissues and organs |
| title_fullStr | MXenes as emerging materials to repair electroactive tissues and organs |
| title_full_unstemmed | MXenes as emerging materials to repair electroactive tissues and organs |
| title_short | MXenes as emerging materials to repair electroactive tissues and organs |
| title_sort | mxenes as emerging materials to repair electroactive tissues and organs |
| topic | MXenes Biosensors Tissue engineering Electroactive |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X2500043X |
| work_keys_str_mv | AT keshavnarayanalagarsamy mxenesasemergingmaterialstorepairelectroactivetissuesandorgans AT leenaregisaleth mxenesasemergingmaterialstorepairelectroactivetissuesandorgans AT saravanansekaran mxenesasemergingmaterialstorepairelectroactivetissuesandorgans AT laurafusco mxenesasemergingmaterialstorepairelectroactivetissuesandorgans AT luciagemmadelogu mxenesasemergingmaterialstorepairelectroactivetissuesandorgans AT maksympogorielov mxenesasemergingmaterialstorepairelectroactivetissuesandorgans AT acelyayilmazer mxenesasemergingmaterialstorepairelectroactivetissuesandorgans AT sanjivdhingra mxenesasemergingmaterialstorepairelectroactivetissuesandorgans |