Kidney transplantation in the presence of pulmonary hypertension: A clinical dilemma
End-stage renal disease (ESRD) is a progressive chronic condition that is strongly associated with cardiovascular mortality. ESRD patients usually benefit significantly from kidney transplantation. Pulmonary hypertension (PH) is a common finding in ESRD patients that adversely affects their survival...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-10-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024151055 |
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| author | Melina Farshbafnadi Rad Ghannadzadeh Kermani Pour Roya Sattarzadeh Badkoubeh Babak Geraiely Maryam Mehrpooya Farnoosh Larti |
| author_facet | Melina Farshbafnadi Rad Ghannadzadeh Kermani Pour Roya Sattarzadeh Badkoubeh Babak Geraiely Maryam Mehrpooya Farnoosh Larti |
| author_sort | Melina Farshbafnadi |
| collection | DOAJ |
| description | End-stage renal disease (ESRD) is a progressive chronic condition that is strongly associated with cardiovascular mortality. ESRD patients usually benefit significantly from kidney transplantation. Pulmonary hypertension (PH) is a common finding in ESRD patients that adversely affects their survival. It has also been associated with adverse increased mortality and morbidity following kidney transplantation. However, PH has also been thought to improve following kidney transplantation. The exact underlying pathophysiology of PH in ESRD patients is unknown. However, it has been believed to be multifactorial, involving endothelial dysfunction, volume overload, and arteriovenous fistula. Management of PH in kidney transplant candidates and ESRD patients is remarkably understudied. Several treatment options are available for the treatment of PH. However, studies conducted on treating PH in ESRD patients are scarce. There is an increased need for studies on ESRD patients with PH. |
| format | Article |
| id | doaj-art-87872ff21ed44f64ab45127fd747d22a |
| institution | OA Journals |
| issn | 2405-8440 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-87872ff21ed44f64ab45127fd747d22a2025-08-20T02:14:03ZengElsevierHeliyon2405-84402024-10-011020e3907410.1016/j.heliyon.2024.e39074Kidney transplantation in the presence of pulmonary hypertension: A clinical dilemmaMelina Farshbafnadi0Rad Ghannadzadeh Kermani Pour1Roya Sattarzadeh Badkoubeh2Babak Geraiely3Maryam Mehrpooya4Farnoosh Larti5School of Medicine, Tehran University of Medical Sciences, Tehran, IranSchool of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Cardiology, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Cardiology, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Cardiology, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Cardiology, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Corresponding author. Department of Cardiology, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.End-stage renal disease (ESRD) is a progressive chronic condition that is strongly associated with cardiovascular mortality. ESRD patients usually benefit significantly from kidney transplantation. Pulmonary hypertension (PH) is a common finding in ESRD patients that adversely affects their survival. It has also been associated with adverse increased mortality and morbidity following kidney transplantation. However, PH has also been thought to improve following kidney transplantation. The exact underlying pathophysiology of PH in ESRD patients is unknown. However, it has been believed to be multifactorial, involving endothelial dysfunction, volume overload, and arteriovenous fistula. Management of PH in kidney transplant candidates and ESRD patients is remarkably understudied. Several treatment options are available for the treatment of PH. However, studies conducted on treating PH in ESRD patients are scarce. There is an increased need for studies on ESRD patients with PH.http://www.sciencedirect.com/science/article/pii/S2405844024151055Pulmonary hypertensionEnd-stage renal diseaseChronic kidney diseaseKidney transplantationOutcomeManagement |
| spellingShingle | Melina Farshbafnadi Rad Ghannadzadeh Kermani Pour Roya Sattarzadeh Badkoubeh Babak Geraiely Maryam Mehrpooya Farnoosh Larti Kidney transplantation in the presence of pulmonary hypertension: A clinical dilemma Heliyon Pulmonary hypertension End-stage renal disease Chronic kidney disease Kidney transplantation Outcome Management |
| title | Kidney transplantation in the presence of pulmonary hypertension: A clinical dilemma |
| title_full | Kidney transplantation in the presence of pulmonary hypertension: A clinical dilemma |
| title_fullStr | Kidney transplantation in the presence of pulmonary hypertension: A clinical dilemma |
| title_full_unstemmed | Kidney transplantation in the presence of pulmonary hypertension: A clinical dilemma |
| title_short | Kidney transplantation in the presence of pulmonary hypertension: A clinical dilemma |
| title_sort | kidney transplantation in the presence of pulmonary hypertension a clinical dilemma |
| topic | Pulmonary hypertension End-stage renal disease Chronic kidney disease Kidney transplantation Outcome Management |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024151055 |
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