Peroxisomal Import Reduces the Proapoptotic Activity of Deubiquitinating Enzyme USP2.

The human deubiquitinating enzyme ubiquitin-specific protease 2 (USP2) regulates multiple cellular pathways, including cell proliferation and apoptosis. As a result of alternative splicing four USP2 isoenzymes are expressed in human cells of which all contain a weak peroxisome targeting signal of ty...

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Bibliographic Details
Main Authors: Katharina Reglinski, Marina Keil, Sabrina Altendorf, Dominic Waithe, Christian Eggeling, Wolfgang Schliebs, Ralf Erdmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0140685
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