Peroxisomal Import Reduces the Proapoptotic Activity of Deubiquitinating Enzyme USP2.
The human deubiquitinating enzyme ubiquitin-specific protease 2 (USP2) regulates multiple cellular pathways, including cell proliferation and apoptosis. As a result of alternative splicing four USP2 isoenzymes are expressed in human cells of which all contain a weak peroxisome targeting signal of ty...
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| Main Authors: | Katharina Reglinski, Marina Keil, Sabrina Altendorf, Dominic Waithe, Christian Eggeling, Wolfgang Schliebs, Ralf Erdmann |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0140685 |
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