Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control Study
Purpose: Intima-Media Thickness (IMT), which is frequently evaluated by B-mode ultrasound study, has been proved to be a reliable surrogate marker for atherosclerosis progression and a predictor of upcoming cardiovascular risks. Sonographic changes of intima-media thickness of carotid artery in Has...
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Tehran University of Medical Sciences
2025-01-01
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| Series: | Frontiers in Biomedical Technologies |
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| Online Access: | https://fbt.tums.ac.ir/index.php/fbt/article/view/697 |
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| author | Maryam Alaei Mohamad Ghazanfari Hashemi Seyedeh Nooshin Miratashi Yazdi Mohammad Ali Kaviani Ali Asadifar Sahand Adib Moradi Khazar Adibmoradi Langaroudi Helia Helali Mina Mahboudi Aynaz Gerami |
| author_facet | Maryam Alaei Mohamad Ghazanfari Hashemi Seyedeh Nooshin Miratashi Yazdi Mohammad Ali Kaviani Ali Asadifar Sahand Adib Moradi Khazar Adibmoradi Langaroudi Helia Helali Mina Mahboudi Aynaz Gerami |
| author_sort | Maryam Alaei |
| collection | DOAJ |
| description |
Purpose: Intima-Media Thickness (IMT), which is frequently evaluated by B-mode ultrasound study, has been proved to be a reliable surrogate marker for atherosclerosis progression and a predictor of upcoming cardiovascular risks. Sonographic changes of intima-media thickness of carotid artery in Hashimoto’s thyroiditis and Celiac disease have been investigated separately. In this study we aimed to evaluate the changes in sonographic appearance of the carotid artery and its mural thickness in patients with Hashimoto’s thyroiditis and concomitant Celiac disease, as a surrogate marker of atherosclerosis and a predictor of cardiovascular diseases.
Materials and Methods: A total of 191 patients including 89 patients with only Hashimoto’s thyroiditis, 11 patients with Hashimoto’s thyroiditis and concomitant Celiac disease, and 91 healthy control subjects underwent ultrasound evaluation of intima-media thickness of carotid artery. High resolution B-mode images with a multi-frequency linear probe, were utilized for assessing the IMT.
Results: IMT in the Hashimoto with celiac disease group was 0.72±0.11 and was 0.69±0.09 in the Hashimoto without celiac disease group and was 0.63±0.10 in the control group. IMT showed significant difference between the three groups and was higher in the Hashimoto patients compared to the control group (P-Value=0.039 and 0.028). Moreover, IMT was marginally higher in the Hashimoto patients with celiac disease compared to the Hashimoto patients without celiac disease (P-Value = 0.046).
Conclusion: Patients with Hashimoto’s thyroiditis suffering from concomitant Celiac disease, showed a more increased IMT values compared to other subjects. This can indicate the potential importance and predictive value of ultrasonic IMT evaluation in Celiac disease and Hashimoto’s thyroiditis as a marker of atherosclerosis progression as well as future risk of cardiovascular insults.
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| format | Article |
| id | doaj-art-8770d93204f143d3bd9030e8ec7720ee |
| institution | Kabale University |
| issn | 2345-5837 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Frontiers in Biomedical Technologies |
| spelling | doaj-art-8770d93204f143d3bd9030e8ec7720ee2025-02-09T08:55:58ZengTehran University of Medical SciencesFrontiers in Biomedical Technologies2345-58372025-01-0112110.18502/fbt.v12i1.17735Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control StudyMaryam Alaei0Mohamad Ghazanfari Hashemi1Seyedeh Nooshin Miratashi Yazdi2Mohammad Ali Kaviani3Ali Asadifar4Sahand Adib Moradi5Khazar Adibmoradi Langaroudi6Helia Helali7Mina Mahboudi8Aynaz Gerami9Research Institute for Gastroenterology and Liver Diseases, Taleghani Hospital, Shahid Beheshti Medical University, Tehran, IranCancer institute, Department of Radiology, Tehran university of medical sciences, Tehran, IranAdvanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Radiology, School of Medicine, Kerman University of Medical Sciences, Kerman, IranDepartment of Radiology, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, IranAdvanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, School of Medicine, Shahid Beheshti Medical University, Tehran, IranDepartment of General Surgery, School of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Purpose: Intima-Media Thickness (IMT), which is frequently evaluated by B-mode ultrasound study, has been proved to be a reliable surrogate marker for atherosclerosis progression and a predictor of upcoming cardiovascular risks. Sonographic changes of intima-media thickness of carotid artery in Hashimoto’s thyroiditis and Celiac disease have been investigated separately. In this study we aimed to evaluate the changes in sonographic appearance of the carotid artery and its mural thickness in patients with Hashimoto’s thyroiditis and concomitant Celiac disease, as a surrogate marker of atherosclerosis and a predictor of cardiovascular diseases. Materials and Methods: A total of 191 patients including 89 patients with only Hashimoto’s thyroiditis, 11 patients with Hashimoto’s thyroiditis and concomitant Celiac disease, and 91 healthy control subjects underwent ultrasound evaluation of intima-media thickness of carotid artery. High resolution B-mode images with a multi-frequency linear probe, were utilized for assessing the IMT. Results: IMT in the Hashimoto with celiac disease group was 0.72±0.11 and was 0.69±0.09 in the Hashimoto without celiac disease group and was 0.63±0.10 in the control group. IMT showed significant difference between the three groups and was higher in the Hashimoto patients compared to the control group (P-Value=0.039 and 0.028). Moreover, IMT was marginally higher in the Hashimoto patients with celiac disease compared to the Hashimoto patients without celiac disease (P-Value = 0.046). Conclusion: Patients with Hashimoto’s thyroiditis suffering from concomitant Celiac disease, showed a more increased IMT values compared to other subjects. This can indicate the potential importance and predictive value of ultrasonic IMT evaluation in Celiac disease and Hashimoto’s thyroiditis as a marker of atherosclerosis progression as well as future risk of cardiovascular insults. https://fbt.tums.ac.ir/index.php/fbt/article/view/697UltrasonographyIntima-Media ThicknessCarotid ArteryHashimoto’s ThyroiditisCeliac Disease |
| spellingShingle | Maryam Alaei Mohamad Ghazanfari Hashemi Seyedeh Nooshin Miratashi Yazdi Mohammad Ali Kaviani Ali Asadifar Sahand Adib Moradi Khazar Adibmoradi Langaroudi Helia Helali Mina Mahboudi Aynaz Gerami Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control Study Frontiers in Biomedical Technologies Ultrasonography Intima-Media Thickness Carotid Artery Hashimoto’s Thyroiditis Celiac Disease |
| title | Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control Study |
| title_full | Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control Study |
| title_fullStr | Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control Study |
| title_full_unstemmed | Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control Study |
| title_short | Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control Study |
| title_sort | ultrasonographic assessment of intima media thickness imt as a surrogate of future atherosclerosis and cardiac diseases in patients with hashimoto s thyroiditis and concomitant celiac disease a case control study |
| topic | Ultrasonography Intima-Media Thickness Carotid Artery Hashimoto’s Thyroiditis Celiac Disease |
| url | https://fbt.tums.ac.ir/index.php/fbt/article/view/697 |
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