Primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow-up: Case report and review of the literature

Neuroendocrine carcinomas typically originate from the digestive system and lungs; however, their occurrence in the female genital tract, particularly in the fallopian tube, is exceedingly rare. Currently, there is no established treatment guideline for neuroendocrine neoplasms of the fallopian tube...

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Main Authors: Jun Ma, Yujing Tang, Wei He, Jun Shi
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Gynecologic Oncology Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352578925000177
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author Jun Ma
Yujing Tang
Wei He
Jun Shi
author_facet Jun Ma
Yujing Tang
Wei He
Jun Shi
author_sort Jun Ma
collection DOAJ
description Neuroendocrine carcinomas typically originate from the digestive system and lungs; however, their occurrence in the female genital tract, particularly in the fallopian tube, is exceedingly rare. Currently, there is no established treatment guideline for neuroendocrine neoplasms of the fallopian tube. In this report, we presented a case of small cell neuroendocrine carcinoma of the fallopian tube, with a survival period exceeding 10 years—which is the longest recorded survival among reported cases of fallopian tube neuroendocrine tumors. The patient underwent a standard open radical tumor resection and lymphadenectomy, followed by adjuvant chemotherapy with cisplatin and etoposide, offering valuable evidence for potential standardized treatment approaches in such rare case.
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series Gynecologic Oncology Reports
spelling doaj-art-876ee7584cc24db8a6d53b49486eb5f32025-08-20T02:27:35ZengElsevierGynecologic Oncology Reports2352-57892025-04-015810169210.1016/j.gore.2025.101692Primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow-up: Case report and review of the literatureJun Ma0Yujing Tang1Wei He2Jun Shi3Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127 ChinaDepartment of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127 ChinaDepartment of Pathology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127 ChinaDepartment of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127 China; Corresponding author.Neuroendocrine carcinomas typically originate from the digestive system and lungs; however, their occurrence in the female genital tract, particularly in the fallopian tube, is exceedingly rare. Currently, there is no established treatment guideline for neuroendocrine neoplasms of the fallopian tube. In this report, we presented a case of small cell neuroendocrine carcinoma of the fallopian tube, with a survival period exceeding 10 years—which is the longest recorded survival among reported cases of fallopian tube neuroendocrine tumors. The patient underwent a standard open radical tumor resection and lymphadenectomy, followed by adjuvant chemotherapy with cisplatin and etoposide, offering valuable evidence for potential standardized treatment approaches in such rare case.http://www.sciencedirect.com/science/article/pii/S2352578925000177Neuroendocrine carcinomaFallopian tubeEpithelial tumor
spellingShingle Jun Ma
Yujing Tang
Wei He
Jun Shi
Primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow-up: Case report and review of the literature
Gynecologic Oncology Reports
Neuroendocrine carcinoma
Fallopian tube
Epithelial tumor
title Primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow-up: Case report and review of the literature
title_full Primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow-up: Case report and review of the literature
title_fullStr Primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow-up: Case report and review of the literature
title_full_unstemmed Primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow-up: Case report and review of the literature
title_short Primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow-up: Case report and review of the literature
title_sort primary neuroendocrine carcinoma of the fallopian tube with exceeding 10 years follow up case report and review of the literature
topic Neuroendocrine carcinoma
Fallopian tube
Epithelial tumor
url http://www.sciencedirect.com/science/article/pii/S2352578925000177
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