IRF2BP2 binds to a conserved RxSVI motif of protein partners and regulates megakaryocytic differentiation
Abstract IRF2BP2 is a transcriptional coregulator that plays diverse regulatory roles in various cellular processes in either IRF2-dependent or IRF2-independent manner through interactions with protein partners via its RING domain; however, the underlying molecular mechanisms remain unclear. In this...
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| Main Authors: | Guanchao Wang, Tiantian Lu, Lei Zhang, Jianping Ding |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-54889-5 |
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