Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization

Infertility in patients with reduced ovarian reserve and thin endometrial lining continues to pose a great challenge for successful in vitro fertilization. In the present case, a patient with a thin endometrium and low ovarian reserve resulted in a positive pregnancy with a specific IVF treatment pl...

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Main Authors: Sudhanshu Dakre, Jarul Shrivastava, Namrata Anjankar, Deepti Shrivastava, Aakash More, Shradha M. Ulhe
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_1399_24
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author Sudhanshu Dakre
Jarul Shrivastava
Namrata Anjankar
Deepti Shrivastava
Aakash More
Shradha M. Ulhe
author_facet Sudhanshu Dakre
Jarul Shrivastava
Namrata Anjankar
Deepti Shrivastava
Aakash More
Shradha M. Ulhe
author_sort Sudhanshu Dakre
collection DOAJ
description Infertility in patients with reduced ovarian reserve and thin endometrial lining continues to pose a great challenge for successful in vitro fertilization. In the present case, a patient with a thin endometrium and low ovarian reserve resulted in a positive pregnancy with a specific IVF treatment plan. It included plasma-rich growth factors, growth hormone, supplementation along with some interventional support of endometrial scratching, and assisted hatching. Endometrial scratching and assisted hatching further optimized implantation potential. The use of these interventions hence promoted successful implantation of the embryo that contributed to positive pregnancy outcome and the birth of a healthy baby at 39 weeks. This case showed how individual ongoing comprehensive treatments definitively made a huge difference in the success of reproductive medicine.
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institution Kabale University
issn 0976-4879
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language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-87538a0b680545ac8995c241d79c39b92025-01-13T10:56:10ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S4017S402010.4103/jpbs.jpbs_1399_24Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial OptimizationSudhanshu DakreJarul ShrivastavaNamrata AnjankarDeepti ShrivastavaAakash MoreShradha M. UlheInfertility in patients with reduced ovarian reserve and thin endometrial lining continues to pose a great challenge for successful in vitro fertilization. In the present case, a patient with a thin endometrium and low ovarian reserve resulted in a positive pregnancy with a specific IVF treatment plan. It included plasma-rich growth factors, growth hormone, supplementation along with some interventional support of endometrial scratching, and assisted hatching. Endometrial scratching and assisted hatching further optimized implantation potential. The use of these interventions hence promoted successful implantation of the embryo that contributed to positive pregnancy outcome and the birth of a healthy baby at 39 weeks. This case showed how individual ongoing comprehensive treatments definitively made a huge difference in the success of reproductive medicine.https://journals.lww.com/10.4103/jpbs.jpbs_1399_24embryosin vitro fertilizationoocytessperm
spellingShingle Sudhanshu Dakre
Jarul Shrivastava
Namrata Anjankar
Deepti Shrivastava
Aakash More
Shradha M. Ulhe
Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization
Journal of Pharmacy and Bioallied Sciences
embryos
in vitro fertilization
oocytes
sperm
title Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization
title_full Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization
title_fullStr Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization
title_full_unstemmed Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization
title_short Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization
title_sort enhancing ivf success in challenging infertility cases the role of prgf gh and endometrial optimization
topic embryos
in vitro fertilization
oocytes
sperm
url https://journals.lww.com/10.4103/jpbs.jpbs_1399_24
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