Palmitoleic acid sensitizes vancomycin-resistant Staphylococcus aureus to vancomycin by outpacing the expression of resistance genes

Palmitoleic acid sensitizes vancomycin-resistant Staphylococcus aureus to vancomycin by outpacing the expression of resistance genes

ABSTRACT The rise in antibiotic resistance limits the availability of antibiotics to treat bacterial infections. Despite this, antibiotic development pipelines remain sparse which makes using adjuvants to reverse antibiotic resistance a promising therapeutic strategy. The use of vancomycin, a frontl...

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Bibliographic Details
Main Authors: Zajeba Tabashsum, Michelle Angeles-Solano, Ashelyn E. Sidders, Joshua B. Parsons, Sarah E. Rowe
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:Microbiology Spectrum
Subjects:
antibiotic resistance
Staphylococcus aureus
antibiotic adjuvants
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01996-24
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