Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study
Background. Pleural effusion (PE) is an important predictor for severity and prognosis of severe acute pancreatitis (SAP). However, there are few studies focused on the effects and timing of indwelling pleural catheter (IPC) on SAP. Considering this, we designed a retrospective study to verify the r...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2022/1919729 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832564062799527936 |
|---|---|
| author | Qian Yao Siyang Peng Yanping Wu Pi Liu |
| author_facet | Qian Yao Siyang Peng Yanping Wu Pi Liu |
| author_sort | Qian Yao |
| collection | DOAJ |
| description | Background. Pleural effusion (PE) is an important predictor for severity and prognosis of severe acute pancreatitis (SAP). However, there are few studies focused on the effects and timing of indwelling pleural catheter (IPC) on SAP. Considering this, we designed a retrospective study to verify the relationship between PE and severity of SAP and observe the effects and timing of IPC in SAP. Methods. A total of 309 SAP patients were enrolled. Based on the presence or absence of PE and IPC and IPC time, the enrolled patients were divided into 6 groups. Then, baseline parameters, disease severity, critical complications, ventilator supporting time (VST), length of stay (LOS), and 60-day mortality were compared between each two groups. Results. PE was a risk factor for death of SAP, but not an independent risk factor. SAP patients with PE rather without PE had higher critical complication rates (p<0.001), along with longer VST (p<0.001) and LOS (p<0.001). And the critical complication rates were lower in group 1 (IPC within 1 week of onset) than group 2 (IPC after 1 week of onset). Further, patients in group 1 also had shorter LOS (p=0.042) and VST (p=0.001) than those in group 2. In addition, the survival analysis showed the risk of death in the PE group was higher than the non-PE group (HR 6.6, 95% CI, 3.67–11.86, and p<0.001). And the risk of death in group 1 was lower than group 2 (HR 0.26, 95% CI, 0.08–0.84, and p=0.025). Conclusions. PE is a risk factor for death of SAP, but not an independent risk factor. IPC, especially IPC within 1 week of onset, has clinical practical value in SAP. |
| format | Article |
| id | doaj-art-873f18d022c34bb4a27a33469a4bfbff |
| institution | Kabale University |
| issn | 1687-630X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-873f18d022c34bb4a27a33469a4bfbff2025-02-03T01:11:54ZengWileyGastroenterology Research and Practice1687-630X2022-01-01202210.1155/2022/1919729Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective StudyQian Yao0Siyang Peng1Yanping Wu2Pi Liu3Department of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyBackground. Pleural effusion (PE) is an important predictor for severity and prognosis of severe acute pancreatitis (SAP). However, there are few studies focused on the effects and timing of indwelling pleural catheter (IPC) on SAP. Considering this, we designed a retrospective study to verify the relationship between PE and severity of SAP and observe the effects and timing of IPC in SAP. Methods. A total of 309 SAP patients were enrolled. Based on the presence or absence of PE and IPC and IPC time, the enrolled patients were divided into 6 groups. Then, baseline parameters, disease severity, critical complications, ventilator supporting time (VST), length of stay (LOS), and 60-day mortality were compared between each two groups. Results. PE was a risk factor for death of SAP, but not an independent risk factor. SAP patients with PE rather without PE had higher critical complication rates (p<0.001), along with longer VST (p<0.001) and LOS (p<0.001). And the critical complication rates were lower in group 1 (IPC within 1 week of onset) than group 2 (IPC after 1 week of onset). Further, patients in group 1 also had shorter LOS (p=0.042) and VST (p=0.001) than those in group 2. In addition, the survival analysis showed the risk of death in the PE group was higher than the non-PE group (HR 6.6, 95% CI, 3.67–11.86, and p<0.001). And the risk of death in group 1 was lower than group 2 (HR 0.26, 95% CI, 0.08–0.84, and p=0.025). Conclusions. PE is a risk factor for death of SAP, but not an independent risk factor. IPC, especially IPC within 1 week of onset, has clinical practical value in SAP.http://dx.doi.org/10.1155/2022/1919729 |
| spellingShingle | Qian Yao Siyang Peng Yanping Wu Pi Liu Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study Gastroenterology Research and Practice |
| title | Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study |
| title_full | Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study |
| title_fullStr | Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study |
| title_full_unstemmed | Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study |
| title_short | Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study |
| title_sort | effects of indwelling pleural catheter on severe acute pancreatitis a retrospective study |
| url | http://dx.doi.org/10.1155/2022/1919729 |
| work_keys_str_mv | AT qianyao effectsofindwellingpleuralcatheteronsevereacutepancreatitisaretrospectivestudy AT siyangpeng effectsofindwellingpleuralcatheteronsevereacutepancreatitisaretrospectivestudy AT yanpingwu effectsofindwellingpleuralcatheteronsevereacutepancreatitisaretrospectivestudy AT piliu effectsofindwellingpleuralcatheteronsevereacutepancreatitisaretrospectivestudy |