Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle
Abstract Medical plastic-appliance-based healthcare services, especially in dentistry, generate tremendous amounts of plastic waste. Given the physiological features of our mouth, it is desirable to substitute dental care plastics with viscoelastic and antimicrobial bioplastics. Herein, we develop a...
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Nature Portfolio
2024-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-53489-7 |
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| author | Woojin Choi Utkarsh Mangal Jae-Hun Yu Jeong-Hyun Ryu Ji‑Yeong Kim Taesuk Jun Yoojin Lee Heesu Cho Moonhyun Choi Milae Lee Du Yeol Ryu Sang-Young Lee Se Yong Jung Jae-Kook Cha Jung Yul Cha Kee-Joon Lee Sangmin Lee Sung-Hwan Choi Jinkee Hong |
| author_facet | Woojin Choi Utkarsh Mangal Jae-Hun Yu Jeong-Hyun Ryu Ji‑Yeong Kim Taesuk Jun Yoojin Lee Heesu Cho Moonhyun Choi Milae Lee Du Yeol Ryu Sang-Young Lee Se Yong Jung Jae-Kook Cha Jung Yul Cha Kee-Joon Lee Sangmin Lee Sung-Hwan Choi Jinkee Hong |
| author_sort | Woojin Choi |
| collection | DOAJ |
| description | Abstract Medical plastic-appliance-based healthcare services, especially in dentistry, generate tremendous amounts of plastic waste. Given the physiological features of our mouth, it is desirable to substitute dental care plastics with viscoelastic and antimicrobial bioplastics. Herein, we develop a medical-grade and sustainable bioplastic that is viscoelastic enough to align the tooth positions, resists microbial contamination, and exhibits recyclable life cycles. In particular, we devise a molecular template involving entanglement-inducing and antimicrobial groups and prepare a silk fibroin-based dental care bioplastic. The generated compactly entangled structure endows great flexibility, toughness, and viscoelasticity. Therefore, a satisfactory orthodontic outcome is accomplished, as demonstrated by the progressive alignment of male rabbit incisors within the 2.5 mm range. Moreover, the prepared bioplastic exhibits resistance to pathogenic colonization of intraoral microbes such as Streptococcaceae and Veillonellaceae. Because the disentanglement of entangled domains enables selective separation and extraction of the components, the bioplastic can be recycled into a mechanically identical one. The proposed medical-grade and sustainable bioplastic could potentially contribute to a green healthcare future. |
| format | Article |
| id | doaj-art-873e43ef0c514aeba3061c172ea2d63b |
| institution | OA Journals |
| issn | 2041-1723 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-873e43ef0c514aeba3061c172ea2d63b2025-08-20T02:11:18ZengNature PortfolioNature Communications2041-17232024-10-0115111410.1038/s41467-024-53489-7Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycleWoojin Choi0Utkarsh Mangal1Jae-Hun Yu2Jeong-Hyun Ryu3Ji‑Yeong Kim4Taesuk Jun5Yoojin Lee6Heesu Cho7Moonhyun Choi8Milae Lee9Du Yeol Ryu10Sang-Young Lee11Se Yong Jung12Jae-Kook Cha13Jung Yul Cha14Kee-Joon Lee15Sangmin Lee16Sung-Hwan Choi17Jinkee Hong18Department of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityBK21 FOUR Project, Yonsei University College of DentistryDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of DentistryDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of DentistryDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of DentistryDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityDepartment of Pediatrics, Yonsei University College of MedicineDepartment of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of DentistryDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of DentistryDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of DentistrySchool of Mechanical Engineering, Chung-ang University, 84, Heukserok-ro, Dongjak-guDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of DentistryDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei UniversityAbstract Medical plastic-appliance-based healthcare services, especially in dentistry, generate tremendous amounts of plastic waste. Given the physiological features of our mouth, it is desirable to substitute dental care plastics with viscoelastic and antimicrobial bioplastics. Herein, we develop a medical-grade and sustainable bioplastic that is viscoelastic enough to align the tooth positions, resists microbial contamination, and exhibits recyclable life cycles. In particular, we devise a molecular template involving entanglement-inducing and antimicrobial groups and prepare a silk fibroin-based dental care bioplastic. The generated compactly entangled structure endows great flexibility, toughness, and viscoelasticity. Therefore, a satisfactory orthodontic outcome is accomplished, as demonstrated by the progressive alignment of male rabbit incisors within the 2.5 mm range. Moreover, the prepared bioplastic exhibits resistance to pathogenic colonization of intraoral microbes such as Streptococcaceae and Veillonellaceae. Because the disentanglement of entangled domains enables selective separation and extraction of the components, the bioplastic can be recycled into a mechanically identical one. The proposed medical-grade and sustainable bioplastic could potentially contribute to a green healthcare future.https://doi.org/10.1038/s41467-024-53489-7 |
| spellingShingle | Woojin Choi Utkarsh Mangal Jae-Hun Yu Jeong-Hyun Ryu Ji‑Yeong Kim Taesuk Jun Yoojin Lee Heesu Cho Moonhyun Choi Milae Lee Du Yeol Ryu Sang-Young Lee Se Yong Jung Jae-Kook Cha Jung Yul Cha Kee-Joon Lee Sangmin Lee Sung-Hwan Choi Jinkee Hong Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle Nature Communications |
| title | Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle |
| title_full | Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle |
| title_fullStr | Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle |
| title_full_unstemmed | Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle |
| title_short | Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle |
| title_sort | viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle |
| url | https://doi.org/10.1038/s41467-024-53489-7 |
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