A prediction model for predicting relapsed-free survival of early-stage invasive breast cancer patients with hormone receptor positive based on Ki67, HER2 and TOP2A

A prediction model for predicting relapsed-free survival of early-stage invasive breast cancer patients with hormone receptor positive based on Ki67, HER2 and TOP2A

ObjectiveThe purpose of the current study was to determine the relationship between ribonucleotide reductase M1 (RRM1), topoisomerase II alpha (TOP2A), Thymidylate synthase (TYMS), class III beta-tubulin (TUBB3) and phosphatase and tensin homolog (PTEN) expressions and relapse-free survival (RFS) in...

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Bibliographic Details
Main Authors: Dawei Yuan, Rulan Ma, Haixia Ye, Wenbo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
invasive breast cancer
hormone receptor positive
relapse-free survival
TOP2A
nomogram
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1552937/full
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