Occurrence and Antibiotics susceptibility profile of Staphylococcus aureus in Chronic skin Ulcer patients attending a Specialist Public healthcare Hospital at Chanchaga Local Government Area, Minna, Niger state, Nigeria
Staphylococcus aureus is a non-motile gram positive bacterium that is responsible for a large amount of disease in humans and animals. The objective of this paper is to evaluate the occurrence and antibiotics susceptibility profile of Staphylococcus aureus in Chronic skin Ulcer patients attending a...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)
2024-12-01
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| Series: | Journal of Applied Sciences and Environmental Management |
| Subjects: | |
| Online Access: | https://www.Ajol.Info/index.php/jasem/article/view/284535 |
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| Summary: | Staphylococcus aureus is a non-motile gram positive bacterium that is responsible for a large amount of disease in humans and animals. The objective of this paper is to evaluate the occurrence and antibiotics susceptibility profile of Staphylococcus aureus in Chronic skin Ulcer patients attending a Specialist Public healthcare Hospital at Chanchaga Local Government Area, Minna, Niger state, Nigeria using appropriate standard methods. The results obtained indicated that Staphylococcus aureus predominates with thirty- four (34)(89.5%) isolates, while Staphylococcus epidermidis was found to be four (4)(10.5 %) isolates. Antibiotic sensitivity testing revealed high resistance of S. aureus isolates to Zinacef (91%), Amoxacillin (94%), while S. epidermidis isolates showed total resistance to Ampiclox (100%), Amoxacillin (100%),Zinacef (100%) and Rocephine(100%). Staphylococcus aureus and Staphylococcus epidermidis isolates showed total (100%) susceptibility to Pefloxacin, Gentamicin and Ciprofloxacin antibiotics. Multi-drug resistant (MDR) patterns were also detected among the isolates of Staphylococcus aureus and Staphylococcus epidermidis. This study concludes that understanding the resistance patterns is critical for guiding effective treatment strategies and warrant continual surveillance to reduce the escalating threat of antibiotic resistant Staphylococcus infection in chronic skin ulcer among patients. It was recommended that the overuse and misuse of antimicrobial agent should be stopped.
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| ISSN: | 2659-1502 2659-1499 |