An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension

We present the case of a 4-year-old boy who was admitted to hospital with intracranial hypertension, headache, diplopia, papilledema, and a normal brain MRI. Brucella melitensis in the cerebrospinal fluid was confirmed with PCR assay. We believe that neurobrucellosis should be included in the differ...

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Main Authors: Xenophon Sinopidis, Joseph Kaleyias, Konstantina Mitropoulou, Maria Triga, Sanjeev V. Kothare, Stefanos Mantagos
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2012/492467
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author Xenophon Sinopidis
Joseph Kaleyias
Konstantina Mitropoulou
Maria Triga
Sanjeev V. Kothare
Stefanos Mantagos
author_facet Xenophon Sinopidis
Joseph Kaleyias
Konstantina Mitropoulou
Maria Triga
Sanjeev V. Kothare
Stefanos Mantagos
author_sort Xenophon Sinopidis
collection DOAJ
description We present the case of a 4-year-old boy who was admitted to hospital with intracranial hypertension, headache, diplopia, papilledema, and a normal brain MRI. Brucella melitensis in the cerebrospinal fluid was confirmed with PCR assay. We believe that neurobrucellosis should be included in the differential diagnosis when headaches persist following brucellosis. In addition, we suggest that when cerebrospinal fluid culture is negative, PCR may prove to be an optimal alternative tool for an immediate and accurate diagnosis.
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publishDate 2012-01-01
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series Case Reports in Infectious Diseases
spelling doaj-art-8730745c48bc443e8177a5b80fc7d2312025-08-20T03:38:01ZengWileyCase Reports in Infectious Diseases2090-66252090-66332012-01-01201210.1155/2012/492467492467An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial HypertensionXenophon Sinopidis0Joseph Kaleyias1Konstantina Mitropoulou2Maria Triga3Sanjeev V. Kothare4Stefanos Mantagos5Department of Pediatric Surgery, Patras University Hospital, University of Patras Medical School, Patras 26504, GreeceDepartment of Pediatrics, Patras University Hospital, University of Patras Medical School, Patras 26504, GreeceDepartment of Pediatrics, Patras University Hospital, University of Patras Medical School, Patras 26504, GreeceDepartment of Pediatrics, Patras University Hospital, University of Patras Medical School, Patras 26504, GreeceDepartment of Neurology, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Pediatrics, Patras University Hospital, University of Patras Medical School, Patras 26504, GreeceWe present the case of a 4-year-old boy who was admitted to hospital with intracranial hypertension, headache, diplopia, papilledema, and a normal brain MRI. Brucella melitensis in the cerebrospinal fluid was confirmed with PCR assay. We believe that neurobrucellosis should be included in the differential diagnosis when headaches persist following brucellosis. In addition, we suggest that when cerebrospinal fluid culture is negative, PCR may prove to be an optimal alternative tool for an immediate and accurate diagnosis.http://dx.doi.org/10.1155/2012/492467
spellingShingle Xenophon Sinopidis
Joseph Kaleyias
Konstantina Mitropoulou
Maria Triga
Sanjeev V. Kothare
Stefanos Mantagos
An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension
Case Reports in Infectious Diseases
title An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension
title_full An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension
title_fullStr An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension
title_full_unstemmed An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension
title_short An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension
title_sort uncommon case of pediatric neurobrucellosis associated with intracranial hypertension
url http://dx.doi.org/10.1155/2012/492467
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