Hepatitis C Virus Core Protein Transforms Murine Fibroblasts by Promoting Genomic Instability

Hepatitis C Virus Core Protein Transforms Murine Fibroblasts by Promoting Genomic Instability

The oncogenic potential of hepatitis C virus (HCV) core protein has been demonstrated, but the precise mechanism of cell transformation triggered by HCV core is still unclear. This study shows that constitutive expression of HCV core protein (core) in NIH 3T3 murine fibroblasts triggers malignant tr...

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Main Authors: Irina S. Smirnova, Nikolai D. Aksenov, Elena V. Kashuba, Pawan Payakurel, Vadim V. Grabovetsky, Alexei D. Zaberezhny, Maxim S. Vonsky, Lubov Buchinska, Peter Biberfeld, Jorma Hinkula, Maria G. Isaguliants
Format: Article
Language:English
Published: Wiley 2006-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2006/864648
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