Integrated Multiomics Analysis and Machine Learning Approaches in Bladder Cancer: Unveiling the Impact of Immunogenic Cell Death and Its Key Gene SLC2A3 on Prognosis and Personalized Treatment Strategies

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Main Authors: Mouyuan Sun, Quanjie Zhang, Zhixu He, Yaxian Luo, Yan Tu, Lianjie Peng, Huchao Mao, Jingyu Zhang, Tao Qiu, Yan Zhang
Format: Article
Language:English
Published: American Chemical Society 2025-06-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.5c01496
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author Mouyuan Sun
Quanjie Zhang
Zhixu He
Yaxian Luo
Yan Tu
Lianjie Peng
Huchao Mao
Jingyu Zhang
Tao Qiu
Yan Zhang
author_facet Mouyuan Sun
Quanjie Zhang
Zhixu He
Yaxian Luo
Yan Tu
Lianjie Peng
Huchao Mao
Jingyu Zhang
Tao Qiu
Yan Zhang
author_sort Mouyuan Sun
collection DOAJ
format Article
id doaj-art-8721f19dcc554d3ab23301a5448fa5be
institution DOAJ
issn 2470-1343
language English
publishDate 2025-06-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-8721f19dcc554d3ab23301a5448fa5be2025-08-20T03:21:27ZengAmerican Chemical SocietyACS Omega2470-13432025-06-011023246552467410.1021/acsomega.5c01496Integrated Multiomics Analysis and Machine Learning Approaches in Bladder Cancer: Unveiling the Impact of Immunogenic Cell Death and Its Key Gene SLC2A3 on Prognosis and Personalized Treatment StrategiesMouyuan Sun0Quanjie Zhang1Zhixu He2Yaxian Luo3Yan Tu4Lianjie Peng5Huchao Mao6Jingyu Zhang7Tao Qiu8Yan Zhang9Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, School of Stomatology, Zhejiang Universit School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, ChinaDepartment of Urology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaEngineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, School of Stomatology, Zhejiang Universit School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, ChinaEngineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, School of Stomatology, Zhejiang Universit School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, ChinaEngineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, School of Stomatology, Zhejiang Universit School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, ChinaEngineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, School of Stomatology, Zhejiang Universit School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, ChinaDepartment of Urology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaEngineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, School of Stomatology, Zhejiang Universit School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, ChinaEngineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, School of Stomatology, Zhejiang Universit School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, ChinaDepartment of Urology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Chinahttps://doi.org/10.1021/acsomega.5c01496
spellingShingle Mouyuan Sun
Quanjie Zhang
Zhixu He
Yaxian Luo
Yan Tu
Lianjie Peng
Huchao Mao
Jingyu Zhang
Tao Qiu
Yan Zhang
Integrated Multiomics Analysis and Machine Learning Approaches in Bladder Cancer: Unveiling the Impact of Immunogenic Cell Death and Its Key Gene SLC2A3 on Prognosis and Personalized Treatment Strategies
ACS Omega
title Integrated Multiomics Analysis and Machine Learning Approaches in Bladder Cancer: Unveiling the Impact of Immunogenic Cell Death and Its Key Gene SLC2A3 on Prognosis and Personalized Treatment Strategies
title_full Integrated Multiomics Analysis and Machine Learning Approaches in Bladder Cancer: Unveiling the Impact of Immunogenic Cell Death and Its Key Gene SLC2A3 on Prognosis and Personalized Treatment Strategies
title_fullStr Integrated Multiomics Analysis and Machine Learning Approaches in Bladder Cancer: Unveiling the Impact of Immunogenic Cell Death and Its Key Gene SLC2A3 on Prognosis and Personalized Treatment Strategies
title_full_unstemmed Integrated Multiomics Analysis and Machine Learning Approaches in Bladder Cancer: Unveiling the Impact of Immunogenic Cell Death and Its Key Gene SLC2A3 on Prognosis and Personalized Treatment Strategies
title_short Integrated Multiomics Analysis and Machine Learning Approaches in Bladder Cancer: Unveiling the Impact of Immunogenic Cell Death and Its Key Gene SLC2A3 on Prognosis and Personalized Treatment Strategies
title_sort integrated multiomics analysis and machine learning approaches in bladder cancer unveiling the impact of immunogenic cell death and its key gene slc2a3 on prognosis and personalized treatment strategies
url https://doi.org/10.1021/acsomega.5c01496
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