Age-specific effects of synthetic cannabinoids on cognitive function and hippocampal gene expression in mice: insights from behavioral and molecular correlates

Age-specific effects of synthetic cannabinoids on cognitive function and hippocampal gene expression in mice: insights from behavioral and molecular correlates

The increasing use of Synthetic cannabinoids (SCs) in adolescents and young adults poses significant medical and psychiatric risks, and previous reports have been dominated by single-age animal studies. Here, we first investigated the effects of a single exposure of the fourth-generation synthetic c...

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Bibliographic Details
Main Authors: Kaixi Li, Yuanyuan Chen, Yawen Xu, Yuan Pang, Yongli Bao, Simeng Zhang, Xuesong Shi, Jingzhi Ran, Yanling Qiao, Yizhao Xu, Yiming Wang, Bin Di, Peng Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
adolescent
synthetic cannabinoids
memory
transcriptomics
4F-ABUTINACA
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1618929/full
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