Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices
The highly selective enrichment and sensitive detection of antibiotics in food are crucial for human health, environmental monitoring, and management. In this study, deep eutectic solvents (DESs) were used as eco–friendly functional monomers, a magnetic molecular nanomaterial (DES–MMIP) coupled with...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Food Chemistry: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157525000483 |
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| author | Yanqiong Luo Han Zhang Jun Liu Aleeza Jamil Yujiao Hou Qian Li Min Zhao Chunjie Zhao Wenjing Li Bo Hong |
| author_facet | Yanqiong Luo Han Zhang Jun Liu Aleeza Jamil Yujiao Hou Qian Li Min Zhao Chunjie Zhao Wenjing Li Bo Hong |
| author_sort | Yanqiong Luo |
| collection | DOAJ |
| description | The highly selective enrichment and sensitive detection of antibiotics in food are crucial for human health, environmental monitoring, and management. In this study, deep eutectic solvents (DESs) were used as eco–friendly functional monomers, a magnetic molecular nanomaterial (DES–MMIP) coupled with carbon dots (CDs) was developed as a sensitive fluorescent probe for the selective enrichment and detection of trace amounts of doxycycline (DOX). Under optimal conditions, the method exhibited good linearity within 0.5–50 μg·L−1, a low detection limit of 0.34 nM for DOX detection. Furthermore, the DES–MMIP displayed excellent reusability and storage stability. With responsive, excellent selectivity and an eco–friendly nature, the established method is successful in detecting DOX in food matrices, with an average spiked recovery of 87.5 %–97.8 %. This strategy of integrating CDs and DES–MMIP for DOX detection conforms to the green concept of environmental protection and provides a new material and research approach for efficient analysis of DOX in complex matrices. |
| format | Article |
| id | doaj-art-871f8394fa884f9d911d28102034d51f |
| institution | Kabale University |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-871f8394fa884f9d911d28102034d51f2025-02-12T05:32:33ZengElsevierFood Chemistry: X2590-15752025-01-0125102202Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matricesYanqiong Luo0Han Zhang1Jun Liu2Aleeza Jamil3Yujiao Hou4Qian Li5Min Zhao6Chunjie Zhao7Wenjing Li8Bo Hong9School of Pharmacy, Qiqihar Medical University, Qiqihar 161003, ChinaSchool of Pharmacy, Qiqihar Medical University, Qiqihar 161003, ChinaSchool of Pharmacy, Qiqihar Medical University, Qiqihar 161003, ChinaSchool of Pharmacy, Qiqihar Medical University, Qiqihar 161003, ChinaSchool of Pharmacy, Qilu Institute of Technology, Jinan 250000, ChinaSchool of Pharmacy, Qiqihar Medical University, Qiqihar 161003, ChinaSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, ChinaSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, ChinaSchool of Pharmacy, Qiqihar Medical University, Qiqihar 161003, China; Corresponding authors.School of Pharmacy, Qiqihar Medical University, Qiqihar 161003, China; Corresponding authors.The highly selective enrichment and sensitive detection of antibiotics in food are crucial for human health, environmental monitoring, and management. In this study, deep eutectic solvents (DESs) were used as eco–friendly functional monomers, a magnetic molecular nanomaterial (DES–MMIP) coupled with carbon dots (CDs) was developed as a sensitive fluorescent probe for the selective enrichment and detection of trace amounts of doxycycline (DOX). Under optimal conditions, the method exhibited good linearity within 0.5–50 μg·L−1, a low detection limit of 0.34 nM for DOX detection. Furthermore, the DES–MMIP displayed excellent reusability and storage stability. With responsive, excellent selectivity and an eco–friendly nature, the established method is successful in detecting DOX in food matrices, with an average spiked recovery of 87.5 %–97.8 %. This strategy of integrating CDs and DES–MMIP for DOX detection conforms to the green concept of environmental protection and provides a new material and research approach for efficient analysis of DOX in complex matrices.http://www.sciencedirect.com/science/article/pii/S2590157525000483Carbon dotsMolecularly imprinted polymersEco–friendly functional monomerDoxycyclineFood matrices |
| spellingShingle | Yanqiong Luo Han Zhang Jun Liu Aleeza Jamil Yujiao Hou Qian Li Min Zhao Chunjie Zhao Wenjing Li Bo Hong Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices Food Chemistry: X Carbon dots Molecularly imprinted polymers Eco–friendly functional monomer Doxycycline Food matrices |
| title | Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices |
| title_full | Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices |
| title_fullStr | Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices |
| title_full_unstemmed | Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices |
| title_short | Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices |
| title_sort | deep eutectic solvent based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices |
| topic | Carbon dots Molecularly imprinted polymers Eco–friendly functional monomer Doxycycline Food matrices |
| url | http://www.sciencedirect.com/science/article/pii/S2590157525000483 |
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