Cross-cohort multi-omics analysis identifies novel clusters driven by EMT signatures in colorectal cancer

Cross-cohort multi-omics analysis identifies novel clusters driven by EMT signatures in colorectal cancer

IntroductionThe pronounced heterogeneity of colorectal cancer (CRC) significantly impacts patient prognosis and therapeutic response, making elucidation of its molecular mechanisms critical for developing precision treatment strategies. This study aimed to systematically characterize tumor cell hete...

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Bibliographic Details
Main Authors:	Wu Ning, Wenqing Jia, Jingyuan Ning, Lei Zhou, Zongze Li, Lin Zhang, Xin Song
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Subjects:	colorectal cancer EMT HOXC6 scRNA-seq metastatic
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1628005/full
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