A Study on Visual Outcome of Patients with Keratoconus after Corneal Collagen Crosslinking
Background and objectives: Cross-linking of the corneal collagen is regarded as a new treatment technique for a non-inflammatory thinning disease of the cornea-known as keratoconus, to strengthen the biomechanical elements of the cornea. Riboflavin (Vit.B2) and UV-A light have been shown to be effec...
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Kurdistan Higher Council Of Medical Specialties
2025-03-01
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| Series: | Advanced Medical Journal |
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| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/593 |
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| author | Ballga Barzan Ahmed Tara Mahmood Hassan Bakhtiar Qadir Hamasalih |
| author_facet | Ballga Barzan Ahmed Tara Mahmood Hassan Bakhtiar Qadir Hamasalih |
| author_sort | Ballga Barzan Ahmed |
| collection | DOAJ |
| description | Background and objectives: Cross-linking of the corneal collagen is regarded as a new treatment technique for a non-inflammatory thinning disease of the cornea-known as keratoconus, to strengthen the biomechanical elements of the cornea. Riboflavin (Vit.B2) and UV-A light have been shown to be effective at stopping progression of keratoconus.
Aim: to evaluate the effects of collagen cross-linking in patients with keratoconus.
Methods: A retrospective, non-controlled study was performed on forty-five patients (64 eyes) with keratoconus in whom collagen crosslinking was done between years (2017-2021). It was conducted in Bright Eye, Tooe Maleek, and the Eye Center private hospitals in sulaimaniya city. We measured the distance visual acuity with and without glasses (Snellen acuity chart and decimal notation), the, the spherical equivalent and cylindrical refractive error (autorefractometer), the central corneal thickness and the mean keratometic reading (corneal topography). These were taken before and after crosslinking in a period between 6-12 months, and then t-test was used to compare and analyze the results.
Results: After comparing the pre- and post-crosslinking findings, we found an improvement in the uncorrected VA (by 0.06±0.04) and best corrected VA (by 0.10±0.03). The central corneal thickness was decreased by a mean of (13±12µm) and the mean keratometric reading decreased by a mean of (0.9D). However, each of the spherical equivalent and cylindrical refractive errors showed no significant difference before and after the procedure (stabilized).
Conclusion: The procedure (collagen crosslinking) was efficacious in stopping progression of the disease. |
| format | Article |
| id | doaj-art-871215bd126a40d1949f180ead64f4d0 |
| institution | Kabale University |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-871215bd126a40d1949f180ead64f4d02025-08-20T03:53:27ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802025-03-011018590https://doi.org/10.56056/amj.2025.321594A Study on Visual Outcome of Patients with Keratoconus after Corneal Collagen CrosslinkingBallga Barzan Ahmed0Tara Mahmood Hassan1Bakhtiar Qadir Hamasalih2MBChB, HD Ophthalmology, trainee of Kurdistan higher council of medical specialties, Sulaimaniyah, IraqMBChB, SMSB, Assistant Professor in Ophthalmology, Sulaimaniyah, IraqMBChB, SMSB, Assistant Professor in Ophthalmology, Sulaimaniyah, IraqBackground and objectives: Cross-linking of the corneal collagen is regarded as a new treatment technique for a non-inflammatory thinning disease of the cornea-known as keratoconus, to strengthen the biomechanical elements of the cornea. Riboflavin (Vit.B2) and UV-A light have been shown to be effective at stopping progression of keratoconus. Aim: to evaluate the effects of collagen cross-linking in patients with keratoconus. Methods: A retrospective, non-controlled study was performed on forty-five patients (64 eyes) with keratoconus in whom collagen crosslinking was done between years (2017-2021). It was conducted in Bright Eye, Tooe Maleek, and the Eye Center private hospitals in sulaimaniya city. We measured the distance visual acuity with and without glasses (Snellen acuity chart and decimal notation), the, the spherical equivalent and cylindrical refractive error (autorefractometer), the central corneal thickness and the mean keratometic reading (corneal topography). These were taken before and after crosslinking in a period between 6-12 months, and then t-test was used to compare and analyze the results. Results: After comparing the pre- and post-crosslinking findings, we found an improvement in the uncorrected VA (by 0.06±0.04) and best corrected VA (by 0.10±0.03). The central corneal thickness was decreased by a mean of (13±12µm) and the mean keratometric reading decreased by a mean of (0.9D). However, each of the spherical equivalent and cylindrical refractive errors showed no significant difference before and after the procedure (stabilized). Conclusion: The procedure (collagen crosslinking) was efficacious in stopping progression of the disease.https://amj.khcms.edu.krd/index.php/main/article/view/593cross-linkingkeratoconuspentacam topography |
| spellingShingle | Ballga Barzan Ahmed Tara Mahmood Hassan Bakhtiar Qadir Hamasalih A Study on Visual Outcome of Patients with Keratoconus after Corneal Collagen Crosslinking Advanced Medical Journal cross-linking keratoconus pentacam topography |
| title | A Study on Visual Outcome of Patients with Keratoconus after Corneal Collagen Crosslinking |
| title_full | A Study on Visual Outcome of Patients with Keratoconus after Corneal Collagen Crosslinking |
| title_fullStr | A Study on Visual Outcome of Patients with Keratoconus after Corneal Collagen Crosslinking |
| title_full_unstemmed | A Study on Visual Outcome of Patients with Keratoconus after Corneal Collagen Crosslinking |
| title_short | A Study on Visual Outcome of Patients with Keratoconus after Corneal Collagen Crosslinking |
| title_sort | study on visual outcome of patients with keratoconus after corneal collagen crosslinking |
| topic | cross-linking keratoconus pentacam topography |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/593 |
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