Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma

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Main Authors: Ingrid Quist-Lokken, Mira Tilseth, Clara Andersson-Rusch, Md Abu Hanif, Michael Walz, Johanna Fredrikke Nordstrand Moen, Megan Anne Vik, Tobias Schmidt Slordahl, Anders Sundan, Felix Hausch, Toril Holien
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-04-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12027
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author Ingrid Quist-Lokken
Mira Tilseth
Clara Andersson-Rusch
Md Abu Hanif
Michael Walz
Johanna Fredrikke Nordstrand Moen
Megan Anne Vik
Tobias Schmidt Slordahl
Anders Sundan
Felix Hausch
Toril Holien
author_facet Ingrid Quist-Lokken
Mira Tilseth
Clara Andersson-Rusch
Md Abu Hanif
Michael Walz
Johanna Fredrikke Nordstrand Moen
Megan Anne Vik
Tobias Schmidt Slordahl
Anders Sundan
Felix Hausch
Toril Holien
author_sort Ingrid Quist-Lokken
collection DOAJ
description Not available.
format Article
id doaj-art-870c8e07147647b0ab9415e8d3121d9f
institution DOAJ
issn 0390-6078
1592-8721
language English
publishDate 2025-04-01
publisher Ferrata Storti Foundation
record_format Article
series Haematologica
spelling doaj-art-870c8e07147647b0ab9415e8d3121d9f2025-08-20T03:18:12ZengFerrata Storti FoundationHaematologica0390-60781592-87212025-04-01999110.3324/haematol.2024.287047Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myelomaIngrid Quist-Lokken0Mira Tilseth1Clara Andersson-Rusch2Md Abu Hanif3Michael Walz4Johanna Fredrikke Nordstrand Moen5Megan Anne Vik6Tobias Schmidt Slordahl7Anders Sundan8Felix Hausch9Toril Holien10Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, TrondheimDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway; Department of Hematology, St. Olav’s University Hospital, TrondheimDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway; Department of Hematology, St. Olav’s University Hospital, TrondheimDepartment of Biomedical Laboratory Science, Norwegian University of Science and Technology - NTNU, TrondheimDepartment of Chemistry, Technical University of Darmstadt, DarmstadtDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, TrondheimDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, TrondheimDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway; Department of Hematology, St. Olav’s University Hospital, TrondheimDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway; Department of Hematology, St. Olav’s University Hospital, TrondheimDepartment of Chemistry, Technical University of Darmstadt, Darmstadt, Germany; Centre for Synthetic Biology, Technical University of Darmstadt, DarmstadtDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway; Department of Hematology, St. Olav’s University Hospital, Trondheim, Norway; Department of Biomedical Laboratory Science, Norwegian University of Science and Technology - NTNU, Trondheim, Norway; Department of Immunology and Transfusion Medicine, St. Olav’s University Hospital, Trondheim Not available. https://haematologica.org/article/view/12027
spellingShingle Ingrid Quist-Lokken
Mira Tilseth
Clara Andersson-Rusch
Md Abu Hanif
Michael Walz
Johanna Fredrikke Nordstrand Moen
Megan Anne Vik
Tobias Schmidt Slordahl
Anders Sundan
Felix Hausch
Toril Holien
Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma
Haematologica
title Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma
title_full Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma
title_fullStr Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma
title_full_unstemmed Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma
title_short Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma
title_sort novel protac to target fkbp12 the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma
url https://haematologica.org/article/view/12027
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