Identification of endothelial INSR as an osteosarcoma-related biomarker and therapeutic target based on weighted gene co-expression network analysis

Abstract Background Osteosarcoma (OS) is the most common primary malignant bone tumor characterized by a high rate of metastasis. The clinical efficacy of current targeted drugs for OS is limited, highlighting the urgent need to identify novel therapeutic targets. The study aimed to identify potenti...

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Bibliographic Details
Main Authors: Xu Yingkai, Jiang Jianfeng, Hu Zhiyong, Zhou Zhifeng, Wang Lei
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-03414-1
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