Genetic determinants of head and neck cancer: exploring causality among immune cells and plasma metabolites through two-sample Mendelian randomization and mediation analysis

Abstract Background Head and neck cancer represents a major health challenge worldwide, characterized by frequent late-stage diagnoses that adversely affect treatment success. The immune system’s cellular components significantly influence the initiation, advancement, and outcome of head and neck ma...

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Bibliographic Details
Main Authors: Yuting Lu, Xiangnan Du, Hanlin Liu, Qing He, Xiaolin Cao
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-025-03181-z
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