Pivotal roles of melanopsin containing retinal ganglion cells in pupillary light reflex in photopic conditions

Pivotal roles of melanopsin containing retinal ganglion cells in pupillary light reflex in photopic conditions

The pupillary light reflex (PLR) is crucial for protecting the retina from excess light. The intrinsically photosensitive retinal ganglion cells (ipRGCs) in the retina are neurons that are critical to generating the PLR, receiving rod/cone photoreceptor signals and directly sensing light through mel...

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Bibliographic Details
Main Authors: Jeremy Matthew Bohl, Abdul Rhman Hassan, Zachary J. Sharpe, Megi Kola, Angela Shehu, Deborah Langrill Beaudoin, Tomomi Ichinose
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
retina
melanopsin ganglion cell
photoreceptor
Cnga3
Gnat1
pupillary light reflex (PLR)
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1547066/full
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